I think it would depend on many factors, not sure about the guidlines thing, all treatments are experimental until they are tried and they had to be tried at some point. I just think there are too many things to be taken into consideration on an individual basis to really come up with one set of guidelines to fit all.
Obviously it must be hard to test some treatments, especially more aggressive ones and unless they are going to throw all ethics and morals out the window they are never going to be able to test a lot of things, not that I am suggesting things go back to how they were before when they did get away with testing on the Jews in concentration camps, prisoners, people in insane asylums, so we are restricted to animal testing which isnt ever going to get results that exactly match how they might affect a human.
One thing Ive learned the last 8 years since getting so sick myself is never say never until you are facing a decision you can never know. When I first had an inkling that I might have a brain disorder even knowing that the only treatment was brain surgery I really didnt think Id go through with it, even when I had spoken to the neurosurgeon and we had agreed I could have the surgery I still wasn't sure if I could go through with it and then I did and since it I have said that I dont think I would go through it a second time if it was something that I needed but in reality if it came to it and if it could help I would.
I just think no matter how sure we think we are that we would react in a certain way to something, we can never really be 100% sure until we were there in that moment having to face that ourselves.