Russia through the hidden eye (continuation)

[Lalas]

В России запущены проекты по адаптации регионов к изменениям климата

Четверть проектов, разработанных по программе Агентства стратегических инициатив (АСИ) «Адаптация регионов России к изменениям климата», уже реализуются в регионах. В частности, в Иркутской области применяется решение по повышению эффективности мониторинга пожарной опасности в лесах, в...

asi.ru

Projects to adapt regions to climate change have been launched in Russia

December 26, 2023
A quarter of the projects developed under the Agency for Strategic Initiatives (ASI) program "Adaptation of Russian Regions to Climate Change" are already being implemented in the regions.
...
Digital solutions are essential for adapting to climate change. Geographic information services make it possible to store information and predict climate risks and assess damage from them. A team from the Kaluga Region is developing such a platform. The unification of disparate information systems for the prompt exchange of data on water, forestry, agriculture, transport, and construction will protect residents, develop new and adjust planned environmental protection measures. A similar platform (in fact, a nature-user digital twin of the subject) may be created in other regions of Russia in the future.

The projects developed during the training received feedback and evaluation from representatives of the Ministry of Economic Development of the Russian Federation, the Bank of Russia, the Russian Energy Agency of the Ministry of Energy of the Russian Federation, VEB.RF, Sberbank, Gazprombank, the Israel Institute of Global Climate and Ecology, the Obukhov Institute of Atmospheric Physics of the Russian Academy of Sciences, the Institute of Economic Forecasting of the Russian Academy of Sciences, the National Research University Higher School of Economics, as well as industrial companies and consulting agencies.

"The ASI initiative has become a catalyst for the joint work of scientists, practitioners, and regional leaders. It became possible to start developing solutions for adaptation to climate change in a comprehensive manner, taking into account a variety of aspects, and to involve specialists from scientific and educational organizations, financial organizations, development institutions and companies in this work. We saw an interesting list of priorities, a lot of non-trivial solutions tailored to the specifics of a particular region," said Sergey Sementsov, Head of the Green Economy Department at the Institute for Research and Expertise of VEB.RF.

According to Maxim Evdokimov, Director of the Ecology Division of the Agency for Strategic Initiatives, one of the important results achieved within the framework of the program is the expert community formed in the regions of Russia, consisting of people who are able to systematically analyze the socio-economic development of the regions through the prism of climate change. "The next step is to develop new tools to support the submitted projects. This will help the regions of Russia to effectively adapt to the new conditions," said Maxim Evdokimov following the results of the program.

В Воронеже создали лабораторию, которая к 2030 году на 70% обеспечит рынок электроникой

Она будет работать на базе кафедры физики твердого тела и наноструктур

nauka.tass.ru

A laboratory has been created in Voronezh, which by 2030 will provide the market with 70% of electronics

It will work on the basis of the Department of Solid State Physics and Nanostructures

VORONEZH, December 28, 2023. Voronezh State University (VSU) has created a laboratory of gallium nitride and silicon electronics, for the creation of which a grant of 100 million rubles was received. It is expected that by 2030 the laboratory will cover 70% of the needs of the Russian market for electronic products for the production of portable devices for medicine, robotics, unmanned aerial vehicles (UAVs), drones, and security systems, the press service of the university reported in the Telegram channel.
...

Russian Science Foundation

Новые комплексы иттербия с управляемыми свойствами для медицины и электроники

Ученые из Института общей и неорганической химии им. Н.С. Курнакова РАН и Физического Института им. П.Н. Лебедева РАН синтезировали и исследовали новые устойчивые комплексы редкоземельного металла иттербия, обладающие свойствами молекулярных магнетиков, эффективно люминесцирующие в инфракрасной...

rscf.ru

December 26, 2023

New Ytterbium Complexes with Controllable Properties for Medicine and Electronics

Scientists from the Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences and the Lebedev Physical Institute of the Russian Academy of Sciences have synthesized and studied new stable complexes of the rare-earth metal ytterbium, which have the properties of molecular magnets and effectively luminesce in the infrared spectral region. The development is promising for the creation of new materials for medicine (for example, luminescent markers) and high-precision electrical engineering (LEDs, materials for recording, processing and storing information). The results of the study were published in the international journal Dalton Transactions.

Novel stable ytterbium acetylacetonate–quinaldinate complexes as single-molecule magnets and surprisingly efficient luminophores

The first Yb complexes comprising a quinoline-2-carboxylate (quinaldinate, Q−) ligand, namely 1D-polymeric [Yb(acac)2(Q)]n (1, acac− is the acetylacetonate (pentane-2,4-dionate) anion) and mononuclear [Yb(acac)2(Q)(Phen)] (2, Phen is 1,10-phenanthroline), are reported. The bifunctionality of...

pubs.rsc.org

The work was supported by a grant from the Russian Science Foundation.

Проект

rscf.ru

ДОМ.РФ и Минстрой России создали экспертную группу по внедрению ИИ в строительной отрасли

Минстрой России совместно с институтом развития ДОМ.РФ создали экспертную группу по внедрению искусственного интеллекта в строительной отрасли. Руководителем…

ru-bezh.ru

DOM.RF and the Ministry of Construction of Russia have created an expert group on the implementation of AI in the construction industry

December 29, 2023
The Ministry of Construction of Russia, together with the DOM.RF Development Institute, created an expert group on the introduction of artificial intelligence in the construction industry.
...

Цифровые аналоги клеток мозга на 20% улучшили "память" нейросетей

Как отмечают ученые, нейросети представляют собой очень упрощенный аналог цепочек нейронов, присутствующих в головном мозге человека и животных

nauka.tass.ru

Digital analogues of brain cells improved the "memory" of neural networks by 20%
As the scientists note, neural networks are a very simplified analogue of the chains of neurons present in the brains of humans and animals

MOSCOW, December 28, 2023. Russian scientists have found that neural networks are much better at remembering information if digital analogues of astrocytes - auxiliary cells of the brain - are embedded in them. Adding such cells to neuromorphic networks has improved their ability to reproduce previously obtained information by 20 percent, the press service of the Russian Science Foundation (RSF) reported on Thursday.

"The model we propose can be used to create a neuromorphic artificial intelligence that works more energy-efficiently than any other algorithms. In addition, our neural network can be used to model the processes occurring in the brain, in particular, the transmission of signals between neurons and astrocytes," explained Susanna Gordleeva, professor at Nizhny Novgorod State University (UNN), whose words are quoted by the press service of the Russian Science Foundation.

As the scientists note, neural networks are a very simplified analogue of the chains of neurons present in the brains of humans and animals. Their simplification is due not only to the incomplete reproduction of all the features in the work of nerve cells, but also to the fact that neural networks lack auxiliary brain cells, the so-called astrocytes and microglia.

Experiments in recent years show that these bodies not only nourish neurons and protect them from infections, but also play an important role in regulating their activity and in remembering new information. With this in mind, the researchers developed a digital analogue of astrocytes that could interact with the rest of the neural network and embedded them into the neuromorphic AI system they were developing.

It consists of three layers, one of which plays the role of analogues of the pyramidal neurons of the brain, which perceive signals; the second consists of semblance of interneurons propagating these signals through the network; and the third is made up of digital astrocytes. Semblance of electrical impulses are transmitted between artificial neurons, and analogues of chemical signals that are emitted by natural cells in the brain are transmitted between astrocytes and neurons.

Subsequent experiments showed that this system was able to successfully recognize images of numbers and letters and reproduce previously received information. In this respect, the neural network with digital astrocytes surpassed its counterpart by 20%, in which these auxiliary cells are absent. This indicates the high prospects of using such an extension of neural networks in the development of neuromorphic AI systems, the researchers concluded.

Московская компания обеспечит чипами собак-поводырей

Столичный производитель RFID-продукции ISBC начал поставлять изделия для чипирования животных в центр обучения собак-поводырей.

www.comnews.ru

Moscow Company to Provide Guide Dogs with Chips

25.12.2023
ISBC, a manufacturer of RFID products in the capital, has begun supplying products for microchipping animals to a training center for guide dogs.

The development will help identify, preserve and improve veterinary care.
...

 

[Lalas]

На острие науки и техники. В Москве прошёл отраслевой форум «Нейротехнологии России 2023»

neuronet.expert

At the forefront of science and technology. The industry forum "Neurotechnologies of Russia 2023" was held in Moscow

29.12.2023

The NeuroNet industry is the most complex technical solutions created at the intersection of engineering and neurobiology. But they are the future, which in one way or another will affect all areas of our lives. The participants of the annual forum "Neurotechnologies of Russia 2023", which brought together all industry participants, expressed absolute confidence in this.

Speakers and guests of the business program were leading Russian developers, engineers, scientists and doctors. The agenda touched upon the development of artificial intelligence, neurotechnologies and neural interfaces. The participants also discussed the "formula for success" of projects in the field of neurotechnology, various nuances and subtleties of the implementation of actively developing projects of the NTI ecosystem in the NeuroNet area, and talked to novice promising developers.

"Neurotechnologies already unite many sectors of the economy and are closely related to technological innovations. For the foreseeable future, they will affect all areas of our lives. Everyone who is associated with the NeuroNet field has this understanding. The goal of the forum is not only to unite community members in the light of economic prospects, but also to form a common approach to the development of neurotechnologies in Russia, to establish interdisciplinary cooperation, and to share scientific and research research. In fact, today the future of the entire industry is being determined here, which is having an increasing impact on our lives every year," said Ivan Biryukov, General Director of the Center for the Development of Social Innovations "Technologies of Opportunities", Head of the Infrastructure Center for NeuroNet 3.0.

The first session was about the market review. The speakers discussed the current situation in the industry and near-term prospects, and also demonstrated the results of current research.

According to Andrey Vilensky, head of the expert group of the Agency for Technological Development, right now, in the context of sanctions pressure on Russia, a window of opportunity for the development of the neuroindustry has appeared in the country.

"This niche will become vacant after the departure of Western companies, and the demand from the state and business, on the contrary, has grown. Now is a great opportunity to implement their projects in the field of neurotechnology for everyone who has thought about it. Even more important is the fact that the existing enterprises working in the NeuroNet direction can multiply their presence in the market, and in the future enter the markets of friendly economies," Andrey Vilensky believes.

According to the expert, neurotechnologies are an end-to-end solution and unite many other industries. Therefore, in the future, they will unite all spheres of our lives, with rare exceptions.

The interdisciplinary nature of neurotechnologies allows them to be applied in the most unexpected places, and, often, some solutions based on them are difficult to attribute to any particular market segment or industry. This is the fate of any end-to-end technology.

Nevertheless, there is an explosive growth of the NeuroNet market around the world, experts say. This is clearly visible in Russia, where in recent years the state and business have shown an increased interest in this area, investments and other cash injections, including from the commercial sector, are increasing.

Other experts agree with Andrei Vilensky. However, despite all the prospects of neurotechnologies, it is not always easy to implement them commercially.

"Today is an era of opportunity. Russia's main task now is to acquire technological sovereignty. It is important to set the right accents and correctly implement the state policy in relation to science. The most difficult stage for our solutions, even the most promising, is commercialization. This is a kind of "valley of death" for many projects on the way from the scientific field to the economic one," said Alexey Streletsky, an expert in the field of NeuroNet.

Meetings of market participants and representatives of development institutions help to partially solve this problem. Such meetings are held annually within the walls of the Neurotechnologies of Russia Forum.

One of the sessions was dedicated to supporting technology projects. The speakers were experienced market participants and representatives of development institutions, who spoke about the specifics of supporting startups, grants and subsidies for business development.

"The problems of investing in neurotechnologies are directly related to the problems of a particular industry. For example, if we are talking about the rehabilitation industry, then solutions based on neurotechnologies in it must be labeled as medical devices, with all the ensuing consequences, including a complex procedure for registering a medical device and the specifics of its further circulation," said Egor Knyazev, Head of the Research and Production Complex, Istok-Audio International.

He also noted that the main customers of neurorehabilitation solutions, as a rule, are rehabilitation clinics. This also has a serious impact on the specifics of support.

"It seems to me that relying solely on the support of the state, it will not be possible to implement even a promising project in the field of neurotechnology. Private investments should be present, at least so that the project has its own mentor from business, who will be directly interested in its development," said Andrey Shcherbinin, Head of the State Program Implementation Division of the Department of Radio-Electronic Industry of the Ministry of Industry and Trade of Russia.

The successful commercialization of projects is partly hampered by the lack of a multidisciplinary base of experts in the Russian segment of the NeuroNet market, who would be able to provide high-quality interdisciplinary analytics, as well as advise business and government.

"Where can we find NeuroNet analysts? After all, the field is interdisciplinary. On the leader-id platform, there is a service for finding experts on the subject "Neuronet". There are many specialists there, but each of them is an expert in their specific field. And we have only six economic segments in the field of neurotechnology, plus technical, regulatory, and many other layers. At the same time, there are not enough integral experts who could understand interdisciplinary questions and answer them competently. If there were at least 20 such integral specialists to contact, it would be useful for the market," said Dmitry Orlov, PhD in Sociology, Deputy Executive Director of Neurotrend JSC.

However, despite all the challenges, the NeuroNet market in Russia is developing and expanding every year. This is due to the increased demand for industries in which neurotechnologies are applied. Among them are developments in the field of artificial intelligence. First of all, we are talking about the use of neural networks, which are already actively used in everyday life. Issues of ethics, safety and responsibility in the use of artificial intelligence were also raised within the walls of the forum.

Experts believe that the use of neural networks and AI-based solutions is something that humanity cannot escape.

"Think of mobile phones. At first, they were used only by the elite, then they became available to everyone. Then, push-button phones evolved into feature-rich smartphones. Or, let's think of conventional computers. In the early 1990s, they were used only in specialized institutions where complex calculations were carried out. And then there was a general demand for personal computers, computer literacy courses for the population, etc. The same will happen with artificial intelligence. And the moment when this technology will become available to everyone is right now," said Alexander Sergeev, General Director of the Federal Center for Applied Development of Artificial Intelligence.

However, despite the increased popularity of neural networks, the expert warned against too high expectations, noting that the level of "hype" around this technology far exceeds its real capabilities. Now it is at the level of experimental use, and only in two or three years a large number of its practical implementations are expected, said Alexander Sergeev.

Today, young scientists, recent university graduates, and education in general play an important role in the development of innovations related to neurotechnologies. It is the research and discoveries of young talents that often lead to technological breakthroughs in medicine, robotics and other high-tech areas.

"It is no coincidence that we have gathered young scientists who are working on invasive interfaces at the forum. These are the most complex, expensive and time-consuming projects in the NeuroNet area. Everything that is introduced into the human body always requires a lot of attention, resources and talent. During the meeting, our guests demonstrated extremely positive trends. They have the resources for further research and an excellent understanding of what to do next – tomorrow, the day after tomorrow, on the horizon of 7 years or more. The development of the industry in almost all areas today lies with such young research groups, and we are happy to maintain contacts with them through universities and departments," Denis Kuleshov, Director of the Sensor-Tech Laboratory, shared the results of the meeting with young talents.

The expert also noted that there are not so many teams in Russia today that are engaged in projects in the field of NeuroNet. Therefore, it is important not to lose the resource you already have. It should be borne in mind that neurotechnologies are very much dependent on industry and infrastructure. They often require modern servers, machine learning systems, as well as equipment for the manufacture of invasive electronics, microchips and flexible structures that can be implanted, Denis Kuleshov emphasized.

One of the areas in which neurotechnologies are used today is unmanned aircraft systems. Solutions based on NeuroNet technologies are already able to provide partial control automation, the use of computer vision and the development of autonomous decision-making systems, which will make drones more efficient and safer.

And in the future, the use of artificial intelligence and neurotechnologies will ensure full automation of UAVs and, at the same time, high-quality control over its operation by humans.

"Biofeedback technologies will work in much the same way as pagers used to work. That is, we will move to 100% automatic control based on AI, but we will receive feedback using neural interfaces. In this way, operators will monitor compliance with AI algorithms, that is, not control, but only control the control of UAVs by artificial intelligence," said Natalia Galkina, Candidate of Biological Sciences, General Director of Neurotrend JSC.

 

[Lalas]

At the end of last year (2022)...

BNNGPT

Elevate Your Search Experience with AI.

bnnbreaking.com

At the end of this (2023) year (the post above)..
"29.12.2023
The NeuroNet industry is the most complex technical solutions created at the intersection of engineering and neurobiology. But they are the future, which in one way or another will affect all areas of our lives. The participants of the annual forum "Neurotechnologies of Russia 2023", which brought together all industry participants, expressed absolute confidence in this.
...
According to Andrey Vilensky, head of the expert group of the Agency for Technological Development, right now, in the context of sanctions pressure on Russia, a window of opportunity for the development of the neuroindustry has appeared in the country."

Russia through the hidden eye

https://rigf.ru/en/ The 13th Russian Internet Governance Forum April 6–7 2023 SUPPORTED BY Ministry of Digital Development, Communications and Mass Media of the Russian Federation ORGANIZERS Russian domains .RU and domain space expertise and https://cgitc.ru/en/ SUSTAINABLE FUTURE OF GLOBAL...

vigilantcitizenforums.com

"The main stages of the development of the Neuronet, Source: Pavel Luksha. Presentation “Roadmap for the development of the Neuronet”, 2014:
BiometriNet (pre-Neuronet) (2014 - 2024)
The onset of the Neuronet (2025 - 2035)
Full-Fledged Neuronet (2035+)
...
When Biometrinet becomes commonplace, the "Neuronet Offensive" will begin (2025-2035), during which communication protocols based on digital models of mental processes will be developed and approaches to organizing a “collective consciousness” capable of “brainstorming” and solving tasks that require the concerted efforts of many people will be found."

 

[Lalas]

Ученые МГУ описали «железосерный контроль качества» в клетках человека

Биологи МГУ с коллегами выявили ранее неизвестный молекулярный механизм, который разрешает биосинтез белков в митохондриях человека только в том случае, если в митохондриях имеется достаточное количество железосерных кластеров, без которых эти белки не могут функционировать нормально.

www.msu.ru

10/01/24, Biology
MSU Scientists Describe "Iron-Sulfur Quality Control" in Human Cells

Researchers from the Faculty of Biology of Moscow State University, together with foreign colleagues, have identified a previously unknown molecular mechanism that allows the biosynthesis of proteins in human mitochondria only if there are a sufficient number of iron-sulfur clusters in the mitochondria, without which these proteins cannot function normally. The scientists' results were published in the journal Molecular Cell on January 9, 2024. The work of Russian researchers was supported by a grant from the Russian Science Foundation.

https://www.sciencedirect.com/science/article/pii/S1097276523010353

...
Results

Loss of FXN leads to a widespread depletion of Fe-S-cluster-containing proteins

We sought to determine the cellular consequences of loss of FXN, an allosteric activator of Fe-S cluster biosynthesis found in the mitochondria. We performed quantitative, whole-proteome profiling of human K562 cells following polyclonal CRISPR-based disruption of FXN versus OR11A1, a non-expressed gene that serves as an editing control, in duplicate.
...
We wondered which of the many genetic pathways downstream of FXN deficiency contribute to the reduced fitness observed in these cells. We performed a genome-wide CRISPR screen.
.....
Acknowledgments
We thank T.L. To, Timothy Durham, Anna V. Kotrys, and John G. Doench for technical assistance and all members of the Mootha lab for fruitful discussions and feedback. This work was supported by the Friedreich’s Ataxia Research Alliance (FARA), the European Research Council (ERC-2018-StG-805230), and the Knut and Alice Wallenberg Foundation (2018.0080). D.L.M.S. acknowledges funding from the National Institutes of Health under award number GM141203. Y.I. was supported by H2020-MSCA-IF-2017 (799399-Itohribo). I.C. and P.K. were supported by RSF [Russian Science Foundation] grant 21-14-00008. Support for the ICP-MS instrument was provided by a core center grant P30-ES002109 from the National Institute of Environmental Health Sciences, NIH. The SciLifeLab cryo-EM facility is funded by the Knut and Alice Wallenberg, Family Erling Persson, and Kempe Foundations. P.R.J. is supported by the National Science Foundation Graduate Research Fellowship Program. V.K.M. is an Investigator of the Howard Hughes Medical Institute."

Глиомные клетки обмениваются генетической информацией с помощью вирус-подобных частиц

Ученые из МФТИ с коллегами выяснили, что клетки глиомы — опухоли мозга — могут обмениваться генетической информацией с помощью вирус-подобных частиц. Они формируются при участии белка вирусного происхождения, который образует капсидные контейнеры для мРНК. Результат исследования поможет...

rscf.ru

January 9, 2024
Glioma cells exchange genetic information with the help of virus-like particles

Scientists from MIPT and their colleagues have found that glioma cells — brain tumors — can exchange genetic information using virus-like particles. They are formed with the participation of a protein of viral origin, which forms capsid containers for mRNA. The result of the study will help to understand the biology of the development of gliomas, the most common and dangerous form of brain cancer. The study was published in the journal Biochimica et Biophysica Acta (BBA) – General Subjects.

Retrovirus-like gag protein Arc/Arg3.1 is involved in extracellular-vesicle-mediated mRNA transfer between glioma cells

Activity-regulated cytoskeleton-associated (Arc) protein is predominantly expressed in excitatory glutamatergic neurons of vertebrates, where it plays…

www.sciencedirect.com

The work was supported by the Russian Science Foundation.

The Arc (Activity-regulated cytoskeleton-associated) protein plays an important regulatory role in the processes of communication between neurons in the brain through special contacts called synapses. The higher the active area of synaptic contacts and the greater the density of receptors on the postsynaptic membrane, the stronger the interneuronal connection. The process of "strengthening" interneuronal contacts plays an important role in mechanisms related to, for example, memory formation and other cognitive functions. Arc can both strengthen and weaken synaptic contacts.

Interestingly, the gene for the Arc protein is viral in origin. It appears to have been "domesticated" in the course of evolution from a group of RNA-containing viruses called retroviruses. The Arc protein is capable of forming capsids, which are protein "containers" for genetic material called mRNA. In this capsid container, mRNA can be transferred from one neuron to another via extracellular vesicles. It is possible that this mechanism also plays a significant role in the formation and regulation of the strength of synaptic contacts.

Synapses aren't just formed between neurons. Recent studies have shown that glioma cells, malignant brain tumors, can also form synapses with neurons. Thanks to the formation of neuroglioma synapses, tumor cells receive biochemical signals that contribute to their survival, stimulate their division and drug resistance.

"In light of these facts, we wondered whether glioma cells can secrete and exchange vesicles with mRNA-containing capsids from the Arc protein in the same way as neurons do," comments Mikhail Durymanov, PhD in Biology, project manager, deputy head of the MIPT Laboratory of Special Cell Technologies.

The scientists found that the Arc protein was highly expressed in several human glioma cell lines. This protein, as well as the mRNA that encodes it, have been found in the extracellular vesicles secreted by glioma cells. The vesicles with Arc capsids themselves differed from other extracellular vesicles in having a smaller diameter comparable to the size of retroviral particles, their production increased significantly in cells with increased Arc expression, and glioma cells with the artificially excised Arc gene did not isolate them. The researchers showed that mRNA-containing vesicles with Arc were able to be taken up by recipient glioma cells by macropinocytosis, after which the mRNA delivered in this way was translated into a functional protein.

"Then we decided to find out how much the identified mechanism of virus-like particle exchange makes to the exchange of mRNA between glioma cells," explains Aya Al Osman, a PhD student at the MIPT Laboratory of Special Cell Technologies.

To answer this question, the scientists obtained cells from the original glioma line that expressed either red fluorescent protein (RFP) or green fluorescent protein (GFP). At the same time, in the "red" cells, the gene encoding the Arc protein was artificially deleted. Of the "green" ones, some were also with the Arc gene turned off, and some were with its increased expression. Next, the "red" cells were cultured together with "green" cells in which Arc expression was either suppressed or enhanced. Since Arc can form complexes and transfer any mRNA into recipient cells, including that encoding GFP, a comparison of the proportion of cells with dual expression of RFP and GFP in the two joint cultures helped to establish the contribution of Arc to mRNA exchange between glioma cells. It turned out that the presence of Arc expression led to a threefold increase in the number of "two-colored" cells. From this, the researchers concluded that the mechanism of information transmission via extracellular vesicles with mRNA/Arc complexes makes a significant contribution to the "communication" of glioma cells with each other.

"It is possible that this mechanism of mRNA exchange involving the Arc protein is possible not only between glioma cells, but also between glioma cells and neurons, which may contribute to the formation of neuroglioma synapses. This hypothesis will have to be tested in the near future," Mikhail Durymanov summed up.

Scientists from the Phystech School of Biological and Medical Physics of MIPT, the Federal Medical and Biological Agency, Lomonosov Moscow State University, and the N.N. Blokhin National Medical Research Oncology Center took part in the work.

Проект

rscf.ru

CARD OF THE FUNDAMENTAL AND EXPLORATORY SCIENTIFIC RESEARCH PROJECT,
SUPPORTED BY THE RUSSIAN SCIENCE FOUNDATION

OVERVIEW

Number: 21-74-00019

Title: Study of Arc/Arg3.1 Protein Delivery in Mammalian Cells
..
Competition: No. 60 - 2021 Competition "Conducting Initiative Research by Young Scientists" of the Presidential Program of Research Projects Implemented by Leading Scientists, Including Young Scientists.

...
Annotation
Despite its attractiveness and promise, gene therapy for various diseases is currently expensive and risky in terms of the safety and efficacy of existing delivery systems. Modern genetic material delivery systems include viral and non-viral vectors. The use of viral systems can be highly effective, but the immunogenicity of viruses severely limits their widespread use. On the other hand, relatively safe and biodegradable synthetic vectors based on lipids and polymers are not as effective compared to viral particles. In addition, both types of vectors have poor permeability in the target tissues, which in turn limits the spread of the delivered nucleic acids to cells distant from the injection site or from the vessels. In early 2018, it was discovered that the endogenous protein Arc (or Arg3.1) from neurons is able to form virus-like capsid structures capable of transferring its own and foreign mRNA between different neurons in the mammalian nervous system as part of exosomes. On the other hand, by themselves (not as part of exosomes), complexes of the Arc protein with mRNA are also able to transfect neurons by overcoming intracellular barriers. Along with safety for the human body, the above properties of the Arc protein 1) can help improve the distribution of the products of the delivered gene in target tissues, and 2) make this protein a promising candidate for gene therapy vectors. In this regard, the goal of this project is to investigate the possibility of using the Arc protein (Arg3.1) to deliver genetic material to cancer cells, which could potentially be used for gene therapy for cancer and other diseases.

Over the past decades, gene therapy for the treatment of various diseases, including cancer, has been actively developing in the world. At the moment, 350 clinical trials of gene therapy approaches to cancer of various localizations clinicaltrials.gov indexed on the website. In the vast majority of cases, viral vectors, mainly adenovirus-based, have been used to deliver genetic material. Despite its efficacy, the use of virus-based carriers of genetic material is not yet safe. There are many scientific papers reporting severe side effects and even fatal cases associated with the immunogenicity of viruses.

According to our hypothesis, the ability of the Arc protein, expressed in the cells of the nervous system, to carry out the transfer of mRNA as part of endosomes between neurons can be used to improve the distribution of the products of the delivered gene in Arc-expressing tissues, for example, in neuroblastoma tumors and some types of gliomas. In addition, a number of preliminary results obtained in our laboratory indicate the possibility of using this property of Arc to improve the transfection of body cells that do not express this protein. To date, several scientific groups are actively studying the Arc protein and its role in neuronal plasticity. Although there have been no applied studies on the use of Arc properties for nucleic acid delivery, a number of reviews have noted the promise of this type of research.


Within the framework of the proposed project, we plan to solve several tasks:

1. To obtain and characterize exosomes with Arc/mRNA from cells with its natural expression, as well as complexes of recombinant Arc with various types of nucleic acids (DNA, mRNA, siRNA).

2. To test the ability of recombinant Arc complexes with different types of nucleic acids, as well as exosomes with Arc/mRNA, to transfect Arc-expressing cells (neuroblastomas and gliomas) and non-Arc-expressing cells (other cancer lines).

3. Study of intracellular transport of Arc/NK and/or exosome complexes with Arc/mRNA in neuroblastoma and glioma cells, as well as in non-Arc expressing cells.

4. To assess the possibility of increasing the efficiency of cell transfection by fusing the reporter gene with the gene of the Arc protein. Evaluation of the efficacy of neuroblastoma cancer cell transfection will be performed in vitro (2D and 3D) and in vivo models with genetic constructs containing 1) the GFP gene and 2) the GFP gene fused with Arc.

5. Creation of a genetic construct of an Arc-fused cytotoxic protein (herpes simplex virus thymidine kinase, HSVtk), transfection of neuroblastoma cancer cells will achieve an improved antitumor effect compared to an Arc-free plasmid. Testing of designs containing HSVtk or Arc-HSVtk on in vitro (2D and 3D) and in vivo models.

We expect that the solution of these tasks and the achievement of the project goal will be the starting point for the development of a new strategy for targeted gene delivery to tumors in the future.


Expected Results
The results expected from the project listed below include a number of aspects of scientific novelty and have a high potential for practical use in the future.

First, we plan to test the ability of recombinant Arc protein complexes with different types of nucleic acids (DNA, mRNA, siRNA) to transfect neurons and cancer cells with neuroblastomas SH-SY5Y, Neuro2A and IMR-32, which have naturally expressed Arc. Previously, this ability was shown for Arc/mRNA complexes on the example of neurons. Experimental evidence of this property of Arc for neuroblastoma cells will provide a rationale for using this strategy to deliver tumor-suppressing nucleic acids.

Secondly, as part of the work, several cell lines that do not have natural Arc expression will be transfected. An important result will be the study of the intracellular localization of the Arc protein, as well as the ability of these cells to exchange vesicles containing Arc with its own or foreign mRNA, similar to neurons. At the moment, one of the studies has demonstrated this ability in the embryonic line HEK293. We were able to reproduce this result in cells of the HEK293 lineage, but it is possible that other cells also have this property. Of particular interest is the study of the process of exosome exchange with Arc/mRNA in 3D cultures, where cells are in close contact.

Third, in order to achieve successful transfection, Arc/NK complexes or exosomes with Arc/mRNA must cross the membrane barrier of the recipient cell. At the moment, it is not known for sure how this happens. We plan to study the mechanisms underlying the transfection of cells by Arc/NK complexes or exosomes with Arc/mRNA, in particular, to determine the role of endocytosis in this process.

To evaluate the anti-cancer efficacy of the strategy using the properties of the Arc protein, we will create a genetic construct of an Arc-fused cytotoxic protein (herpes simplex virus thymidine kinase, HSVtk). We expect that neuroblastoma cells primarily-transfected with this plasmid will "transfer" Arc-HSVtk particles in complex with the mRNA of this chimera to neighboring cells, providing improved propagation of the RNA transcript of the delivered gene into the tumor tissue due to secondarily transfected cells. In a 3D cell and animal model of neuroblastoma, we will compare the transfection and antitumor effect of the construct with an Arc-free plasmid. It should be noted that the assessment of the therapeutic effect of Arc-containing constructs will be carried out for the first time.

We expect that these results will be the starting point for the development of a new safe technology for targeted gene delivery to tumors in the future.
...

Possibility of practical use of the results:
..
Finally, the ability of glioma cells to exchange mRNA with the participation of the virus-like protein Arc, shown in this work, opens up new possibilities for using this protein to deliver genetic material to mammalian cells, which can be used in gene therapy.

В ЕАЭС пройдет конкурс совместных интеграционных проектов «Символы евразийской интеграции»

Новости Агентства стратегических инициатив

asi.ru

The EAEU will host a competition of joint integration projects "Symbols of Eurasian Integration"

January 10, 2024

The Agency for Strategic Initiatives, the Eurasian Economic Commission (EEC) and the Ministry of Economic Development of the Russian Federation have agreed to hold the Symbols of Eurasian Integration competition in 2024. Its goal is to identify new ideas in the technological spheres of Eurasian integration. The organizers will be the Agency for Strategic Initiatives (ASI) and members of the consortium of development institutions, and the co-organizer will be the Eurasian Economic Commission.

"The implementation of joint large-scale high-tech projects by the EAEU States is provided for by the Strategy-2025. We expect that the competition will attract additional attention of enterprises to the advantages of cooperation in the EAEU, will ensure the practical implementation of the integration potential of the Union," said Sergey Glazyev, Minister in charge of Integration and Macroeconomics of the EEC.

Last year, Russia chaired the EAEU bodies. On behalf of Russian President Vladimir Putin, attention was then focused on the development of the technological potential of the EAEU members, digital transformation, strengthening food security, creating common energy markets and forming a new transport and logistics infrastructure."

Ученые МГУ разработали биосенсоры на основе полевых транзисторов

Группа ученых физического, химического факультетов и НИИЯФ МГУ представили систему для детектирования специфичных биообъектов (антитела, аптамеры, олигонуклеотиды), которую можно использовать многократно.

www.msu.ru

27/12/23
MSU Scientists Develop Biosensors Based on Field-Effect Transistors

A group of scientists from the Faculty of Physics, the Faculty of Chemistry and the Institute of Nuclear Physics of Moscow State University presented a system for detecting specific biological objects (antibodies, aptamers, oligonucleotides), which can be used repeatedly.

The research was carried out within the framework of the Interdisciplinary Scientific and Educational School of Moscow State University "Photonic and Quantum Technologies. Digital Medicine". The results of the work were published in the journal "Bulletin of Moscow University".

The sensor itself is a transistor – a device consisting of three electrodes – a drain, a source and a gate. The electric current between the drain and the source is controlled by the voltage at the third electrode, the gate. The difference between the transistor used and the classical one is that the gate is made in the form of a very narrow silicon nanowire (the width of which is 80 nanometers, and the length is 3-5 microns), which makes it possible to detect biological objects with record sensitivity. Heaters and temperature meters were added to the chip with the sensor. Such a thermoregulation system is an important element of the device, thanks to which it is possible to carry out measurements in optimal temperature regimes for each of the detected objects. In addition, it allows you to clean the sensor from biomaterial residues and use it repeatedly.

Interdisciplinary research on the development and creation of nanoscale biosensors based on field-effect transistors with a nanowire channel has been carried out for several years at the Cryoelectronics Laboratory together with the Department of Chemical Enzymology of the Faculty of Chemistry of Moscow State University.

Scientists are developing a system to detect key biochemical biomarkers and drug resistance genes in real time. Detection of biomarkers is carried out using a silicon chip on which very sensitive sensors are created. Such sensors are a field-effect transistor with a nanowire channel. In transistors, the electric current between the drain and the source is controlled by the voltage on the third electrode – the gate (which, with its electric field, "blocks" or, conversely, "opens" the channel of current flow between the drain and the source). In addition, the channel is a very thin nanowire, thanks to which the current flow channel will be extremely sensitive to an external electric field.

In order to detect certain biological objects, special recognition biomolecules – "locks" – are "sewn" to the surface of the nanowire, which grab and hold the necessary biological objects ("keys") near the surface of the nanowire of the sensor. Since almost all biological objects have a non-zero electric charge, the electric field generated by them affects the current through the nanowire. This is how specific biological objects are detected: proteins, viruses, nucleic acids, etc.

The sensitivity of such sensors is extremely high and reaches the level of attomoles, and in some cases it is possible to achieve the detection of single molecules or particles.

"One of the problems of creating DNA sensors is the low selectivity of detection at room temperature and the difficulties with the destruction of complexes for reusable sensors," said one of the authors of the work, Oleg Snigirev, head of the Department of Semiconductor Physics at the Faculty of Physics of Moscow State University. "To solve this problem, a biosensor with a built-in thermostat was developed, which allows incubation and washing at elevated temperatures. As a result, DNA hybridization occurs most efficiently, which increases specificity and avoids false positive results, as well as reduces analysis time. The ability to heat up to 85-90 degrees Celsius makes it possible to use such devices repeatedly."

Москва и Агентство стратегических инициатив будут развивать повестку в области устойчивого развития

Новости Агентства стратегических инициатив

asi.ru

Moscow and the Agency for Strategic Initiatives will develop the sustainable development agenda
January 10, 2024

The Moscow Government and the Agency for Strategic Initiatives (ASI) have signed a partnership agreement in the field of sustainable development and social capital of business. The document was signed on December 28 as part of the final meeting of the Project Office for Improving the Investment Climate in Moscow. This was announced by Vladimir Efimov, Deputy Mayor of Moscow for Economic Policy and Property and Land Relations.

The Center for Assessing the Compliance of Organizations' Activities with the Sustainable Development Goals (SDGs), established by the Moscow government, operates on such principles as a responsible attitude to the environment, high social responsibility and high quality of corporate governance.

"The capital has been involved in the ESG agenda for several years. The city has fully implemented six Sustainable Development Goals and continues to implement projects to ensure the achievement of eight more. These include public-private partnerships, in particular offset contracts. Today, the capital is the leader in terms of the number of signed offsets, there are already 14 of them. Cooperation with the Agency for Strategic Initiatives will ensure the implementation of measures aimed at achieving the SDGs not only in Moscow, but throughout the country," said Vladimir Efimov.

Also, cooperation within the framework of the agreement with the Agency for Strategic Initiatives will contribute to the formation of the right ideas of the business community about the sustainable development agenda and the standard of social capital of business.

"The Agency is developing the standard of social capital of business on behalf of the President of Russia. We expect that the implementation of the standard will motivate businesses to actively participate in social and environmental projects, in initiatives related to improving the quality of life of citizens, and will ensure public recognition of this contribution. The agreement with the Moscow government will allow us to apply the accumulated experience and competencies of the capital in the field of sustainable development and scale them up," said Svetlana Chupsheva, ASI General Director.

In addition, the parties to the agreement will also interact within the framework of the Center for Assessing the Compliance of Organizations' Activities with the SDGs and Improving Management Standards, Transparency of Reporting in the Field of Sustainable Development. It is planned that organizations that have successfully completed the audit will be able to apply for financial and non-financial preferences.

"Moscow has extensive experience and well-established practices in the field of achieving the SDGs, which we are ready to share with all regions of the country. For example, investors who decide to build an industrial enterprise in the capital can go through administrative procedures twice as fast when building a new production facility within the "green corridor". A prerequisite is compliance with strict environmental standards of the facility under construction. We are also implementing a programme to create jobs that will help reduce commuting due to new jobs in different districts of the city," said Vladislav Ovchinsky, Minister of the Moscow Government and Head of the Department of Investment and Industrial Policy.

Moscow became the first region of the country where industrial construction appeared, when construction is carried out not at the facility itself, but at the plant. At the production site, ready-made modules are assembled, after which they are delivered to the site and a building is erected from them. This approach reduces environmental damage.

Today, the city has fully ensured the implementation of indicators for six SDGs, including "Decent Work and Economic Growth", "Quality Education", "Affordable and Clean Energy", "Industry, Innovation and Infrastructure", "Gender Equality", "Combating Climate Change".

 

[Lalas]

Federal State Autonomous Educational Institution of Higher Education "Ural Federal University named after the first President of Russia B.N. Yeltsin"

Стрессоустойчивость рождается в семье

1 июня пройдет прямой эфир в группе VK на тему того, как поведение родителей отражается на стрессоустойчивости детей

psy-urgi.urfu.ru

Results of the International Forum on Cognitive Neuroscience "COGNITITVE NEUROSCIENCE – 2023"
December 15, 2023

We will tell you how the Forum was held from December 7 to 9 at the Ural Institute for the Humanities of UrFU

From December 7 to 9, the Ural Institute for the Humanities of UrFU hosted the sixth annual International Forum on Cognitive Neuroscience "COGNITITVE NEUROSCIENCE – 2023". Despite the abnormal cold, the forum was held in person and brought together more than 300 participants.

The geography of the participants was wide and covered many cities and regions of Russia and the countries of near and far abroad. There were also a considerable number of participants from near and far abroad. Participants from Kyrgyzstan, Belarus, China, Uzbekistan, Kazakhstan, Mongolia, Moldova, Abkhazia, Croatia, Great Britain, and the USA connected online as listeners, as well as to make presentations. A separate pleasant event of this forum was the arrival of two foreign delegations at once. The first is colleagues and partners of the university from the Bukhara State Pedagogical Institute with a reciprocal friendly visit. Also, together with her husband, a graduate of the Faculty of Philosophy of the Ural State University named after A.M. Gorky came from Mongolia.

Traditionally, the forum featured two formats of work that have already become familiar to the participants: lectures by leading Russian and foreign scientists on various topics related to the most pressing issues of modern neuroscience; The work of thematic sections, including reports of face-to-face and online participants, discussions and questions.

The main trend in the scientific field of COGNITITVE NEUROSCIENCE remains unchanged – it is an interdisciplinary approach. In recent years, the scientific topics of the forum have significantly expanded and supplemented with new directions. Initially, the main emphasis was placed on the integration of psychology and medicine, but now the psycholinguistic aspect, neurophilosophy, behavioral economics, neuromarketing, and the development of neural networks are taken into account.

This year, the key reports of the plenary session of the forum highlighted scientific data on the cognitive characteristics of a person in different age periods - from early childhood to old age. Since cognitive functioning and mental health are an integral component of a person's overall well-being, one of the most important problems for modern science is considered here in a comprehensive manner – how to develop and maintain the cognitive functioning of a person at any age and what tools can be used for this.

It is not the first year that the forum has hosted an exhibition of equipment and cognitive methods, organized in cooperation with psychologists from the Ministry of Emergency Situations of Russia. All guests of the forum had the opportunity to get an idea of psychological prevention, correction and rehabilitation in the work of a specialist of the Center for Emergency Psychological Assistance of the Ministry of Emergency Situations of Russia. Participants and guests of the forum noted the importance and effectiveness of psychophysiological equipment with biofeedback, since it is always interesting to learn about one's condition and compare it with one's self-perception. The vibroacoustic chair "Sensorium" was in great demand among the participants, as it allowed them to quickly recuperate in the conditions of a tight conference schedule.

Also, for the second year in a row, a case session was held within the framework of the forum, where representatives of technology startups (Neurotechnology, TriV, STADIKEYS) or already developed large Russian companies from the neurotechnology industry (Neurotrend, NeuroChat) spoke. Obviously, the activities of such companies directly depend on the development of neuroscience and are aimed at the implementation of scientific results in practice. At the case session in the mode of live interaction with the audience, the speakers shared their experience in the successful implementation of technological projects in the fields of medicine and education.

In 2023, one of the main partners of the forum was the Center for Cognitive Technologies of UMMC-Health. It is one of the leading centers in Russia specializing in the cognitive health of patients. On December 9, trainers from UMMC-Health held two master classes, where, together with the participants, they demonstrated the principles of using some techniques for neurocorrection and rehabilitation, as well as the features of the equipment necessary for this: a balance board for training cerebellar functions; Fitlight neurosimulator for creating unique motor tasks using flashlights. Despite the early Saturday morning, the master classes aroused keen interest and a lot of positive emotions among the audience.

Two more master classes, which aroused great interest among the participants, were conducted by employees of the Department of Psychology of UrFU. Maria Aleksandrovna Lavrova, Senior Lecturer at the Department of Clinical Psychology and Psychophysiology, demonstrated a set of exercises for the development of cognitive functions and activation of cognitive activity. Ilona Denisova and Valeria Zakharchenko, students of the Department of Psychology, under the guidance of Lyudmila Tokarskaya, PhD in Psychology, Associate Professor of the Department of Pedagogy and Psychology of Education, taught the forum participants how to use neural networks in the design of psychocorrectional programs, including those aimed at neurocognitive development.

For all three days, there was a palpable warm and hospitable atmosphere at the forum site. Even with abnormally cold weather and the possibility of remote participation, all halls and auditoriums were full. As a result of the event, new interesting projects and collaborations were formed, which will contribute to the development of neuroscience and the neurotechnology market.

Ural Federal University is one of the leading universities in Russia, located in Yekaterinburg. Participant in the project to create world-class campuses, part of the national project "Science and Universities", implemented by the Ministry of Education and Science of the Russian Federation. The university is a member of the state program for the support of Russian universities "Priority-2030", initiates the creation and performs the functions of the project office of the world-class Ural Interregional Research and Education Center "Advanced Production Technologies and Materials".

АНО «Цифровая экономика» приняла участие в рабочей группе «Умный город» при Минстрое России

d-economy.ru

ANO Digital Economy took part in the Smart City working group under the Ministry of Construction of Russia
25.12.2023

At the Russia International Exhibition and Forum, as part of a meeting of the working group on the implementation of the departmental project "Smart City" under the Ministry of Construction, Housing and Utilities of the Russian Federation, Alexey Sidoryuk, Director for Digital Transformation of Industries of the ANO Digital Economy, spoke about the development of the methodological base in terms of the use of artificial intelligence technology and the activities of the ANO CE in the direction of "Smart City, Construction and Housing and Public Utilities".

This year, the Ministry of Construction of the Russian Federation, together with the ANO Digital Economy, conducted a study on the possibilities of using artificial intelligence in modern cities. According to the data obtained, the use of artificial intelligence has a significant impact on improving the quality of life of citizens by providing affordable services, improving urban infrastructure, and reducing the time spent on public transport. One of the leaders in the implementation of smart city solutions is Moscow, where 40% of city systems and services use artificial intelligence algorithms.

The Ministry of Construction of the Russian Federation has been implementing the Smart City project since 2018 as part of the national project "Housing and Urban Environment" and the national program "Digital Economy". Currently, more than 200 cities of Russia are taking part in the implementation of the project. Since 2018, the average IQ index of cities has increased by almost 40%.

"In 2023, a study was conducted on effective practices for implementing artificial intelligence in a smart city. A total of 192 practices were considered, of which 56 were selected for the final report and infographics. Practices for implementing AI solutions are published on the website of the Center for Technological Leadership techlid.rf. Now we continue to work on the coordination of methodological recommendations for assessing readiness for the implementation of AI at the municipal level. In the future, together with the Ministry of Construction of Russia, we plan to adjust the approach to calculating the rating of IQ cities so that it takes into account the practices of introducing AI, and we also plan a study on effective practices for the introduction of artificial intelligence in the construction and housing and utilities sectors for 2024."
Alexey Sidoryuk, Director for Digital Transformation of Industries, Digital Economy

Summing up the results of the project implementation in 2023, Konstantin Mikhailik, Deputy Minister of Construction, Housing and Utilities of the Russian Federation, stressed that digital transformation is a key tool for improving the efficiency of the urban economy and adapting to new challenges, and one of the main principles of the Smart City project is people-centeredness.

"A smart city is a concept and a whole range of solutions aimed at improving the quality of life of our citizens – the comfort and safety of the urban economy, the efficiency of response and the efficiency of decision-making. Cities are developing in terms of infrastructure, services, and the quality of the urban environment. This process must continue."
Konstantin Mikhailik, Deputy Minister of Construction, Housing and Utilities of the Russian Federation

Earlier, ANO Digital Economy, with the support of the Ministry of Construction of Russia, the Ministry of Economic Development of Russia and the Ministry of Digital Development of Russia, developed a map of effective practices for the use of artificial intelligence in a smart city and presented an analytical report "Effective domestic practices based on artificial intelligence technologies in a smart city". These materials demonstrate the positive effect of examples of the use of AI technologies in the Russian Federation.

Карта эффективных практик по использованию искусственного интеллекта в «умном городе»

d-economy.ru

Map of Effective Practices for the Use of Artificial Intelligence in a Smart City

 

[Lalas]

«AI Summit 2024» - конференция про искусственный интеллект для бизнеса

17 февраля 2024 года, в Москве, в Центре международной торговли состоится бизнес-конференция AISUMMIT2024, посвящённая перспективам использования искусственного интеллекта в бизнесе и органах государственной власти.

berza.ru

AI Summit 2024 – Artificial Intelligence for Business Conference

On February 17, 2024, the AISUMMIT2024 business conference will be held in Moscow at the World Trade Center, dedicated to the prospects for the use of artificial intelligence in business and public authorities. The main goal is to demonstrate the possibilities of implementing artificial intelligence to improve business processes, optimize costs, improve the quality of customer service, and reduce the production time of goods and services. A detailed conference program and opportunities for participation are presented on the official website.

The theme of the event is focused on advanced technologies such as robotics, unmanned systems, computer vision in industry and daily activities, as well as speech recognition. The conference will bring together more than 2000 participants, including the heads of the largest companies: Sberbank, Gazpromneft, Avito, Rostelecom, Geoscan, Aeromax; representatives of federal and regional authorities, higher education institutions, investors and experts in the field of new technologies.

The opening of the conference is planned with the participation of Maksut Shadaev, Minister of Digital Development, Communications and Mass Media of the Russian Federation. Recognized experts in the field of artificial intelligence, such as Olga Uskova (CEO of Cognitive Pilot), Alexander Krainov (Director for the Development of Artificial Intelligence Technologies at Yandex), Alexander Baykin (founder of the largest robotics portal PRObotov), as well as representatives of leading companies and other key participants in the artificial intelligence market will speak on the stage.

Конференция «AISUMMIT – Искусственный интеллект для бизнеса» – ведущая платформа для цифровой трансформации вашего бизнеса!

Внедрение нейросетей в бизнес-процессы — это шаг к более умному, эффективному и конкурентоспособному бизнесу. Одно из самых значимых деловых мероприятий в области цифровой экономики России.

aisummit.ru

AI SUMMIT 2024
Artificial intelligence is not the future, but a reality! Unique content from leading experts, demonstration of robotic business processes already used in small and medium-sized companies. Seize the opportunity to make your business stronger...

 

[Lalas]

МВД привлечёт нейросети к поиску правонарушителей

Министерство внутренних дел планирует внедрить искусственный интеллект (ИИ) в правоохранительную деятельность. В 2024 году ведомство собирается провести научно‑исследовательскую работу (НИР)...

habr.com

12.01.2024
The Ministry of Internal Affairs will involve neural networks in the search for offenders

The Ministry of Internal Affairs plans to introduce artificial intelligence (AI) into law enforcement. In 2024, the agency is going to conduct research work and prepare datasets for training and testing neural network models. In 2025, the ministry intends to develop two AI-based systems, Clone and Conjuncture. This is reported by Vedomosti.

"Clone" will make it possible to detect the facts of falsification of video images in the interests of law enforcement, "Conjuncture" should predict negative events and emergencies and simulate scenarios for responding to them.

Such measures are included in the plan for the introduction of AI technologies in the activities of the internal affairs bodies of the Russian Federation for 2023-2025. The plan was approved by Deputy Interior Minister Vitaly Shulika. Vedomosti got acquainted with the document, its authenticity was confirmed by an employee of a large IT integrator working with government contracts.

To implement these plans, special units will be created in the Main Information and Analytical Center (GIAC) and the NGO "Special Equipment and Communications of the Ministry of Internal Affairs of Russia" (NPO STiS) in 2024, the document says. Also, the Department of Information Technology, Communications and Information Protection of the Ministry of Internal Affairs, GIAC and NPO STiS will have to create a data analysis laboratory (sandbox) for modeling and data management by the end of 2024.

There are no ready-made products similar to "Clone" and "Konjunktura" on the Russian market now, says Ruslan Permyakov, Deputy Director of the NTI Competence Center "Technologies of Trusted Interaction" based at TUSUR. There are no complete analogues due to the rather narrow specifics of the tasks to be solved, agrees Svetlana Ivanova, Commercial Director of RDTEX. Any company can be a contractor, but such a development involves access to state secrets, so this requires a special license, Permyakov emphasizes.

Products like Clone and Konjuncture already exist abroad and are used for analysis and forecasting, says Dmitry Parshin, director of the Artezio development center. For example, Clone is reminiscent of the Deepfake Detection Challenge, a service developed by Facebook, Microsoft, and Amazon to detect fake video images using AI. The "conjuncture" is similar to IBM's Watson Openscale service, which is designed to monitor and manage AI models.

The creation of sandboxes, which are specialized environments for safe and effective training of neural network models on large amounts of data, is quite an expected step by the agency, Parshin believes. There are now both public and private data sandboxes. For example, GitHub and Kaggle offer extensive collections that can be used to train neural networks. Most likely, in the case of the Ministry of Internal Affairs, both own and open data can be used, Parshin admitted. This can include text, graphic, video, audio, geographic, biometric and other types of data, the expert suggests.

The Big Data Association (BDA) already has a working sandbox. Now it processes sets of industry datasets and data from open sources, the representative of the association said, refusing to disclose the volume and purpose of using the information. In addition, the association plans to test the use of a sandbox to work with anonymized data as part of the "Trusted Data Broker" experimental legal regime, he added.

The key point in creating datasets is not only to collect data from scratch, but also to be able to reuse data from other agencies collected for other tasks, emphasizes Tatyana Mosendz, an expert at the NTI Neuronet market and development director at EKF. This is due to the fact that the colossal potential for solving problems opens up in the case of the use of collective creation of datasets and algorithms for their processing, she points out."

Comments:

Are we going to the "Guardian Birds" by the right road, comrades?
...
Robots are not yet planned to be involved in eliminating the violation
..
Only to eliminate violators?

The key word is "yet".

...
"The key to creating datasets is not only to collect data from scratch, but also to be able to reuse data from other agencies that have been collected for other purposes."

I immediately recall the eagerness with which banks, without asking too much, collect customers' biometrics and upload them to the UBS [Unified Biometric System]."

РЖД 20 лет

РЖД 20 лет

20rzd.interfax.ru

Over the 20 years of its history, Russian Railways has entered the world's top 3 railway companies. It is the main transport company in Russia, accounting for 47.2% of freight and 25% of passenger traffic in the country. The modernization of railways stimulates the opening of enterprises, the growth of production and the creation of jobs - this is how Russian Railways help the development of the economy.

Thanks to digitalization, the company speeds up transportation, simplifies its registration, increases safety and becomes more efficient.

Digital Solutions for Passengers
Digital technologies make rail travel more comfortable for passengers

Russian Railways Passengers
Previously, train tickets were bought at the station, standing in line at the ticket office. Now in the mobile application or on the website there is a schedule for any station in Russia, from Kaliningrad to Sakhalin. You can buy a ticket online, and when boarding, you can only show your documents. On suburban routes, it is becoming the norm to pay by cards and FPS, and train tickets in Moscow are easily activated via NFC.

76% of tickets are issued electronically
1/3 of long-distance train tickets are bought in the app


Virtual Assistant
The robot answers questions from Russian Railways customers by phone and in chats. Without waiting for free operators, you can find out the schedule, availability and cost of tickets, ask about the rules of the trip, ticket refunds, and more — the robot understands more than 100 topics and learns new ones. He understands the spoken language, and when communicating by voice, he is able to find and voice text information from Russian Railways systems. A virtual assistant takes care of routine issues so that customer support staff can help customers with complex cases faster.

The robot successfully processes 77% of requests without the participation of an operator
50-70% of employees' working time is freed from standard questions
80% of requests in the future should be closed by a robot without the participation of an operator


Digital twins

Training of railway workers in VR

Rails in the blockchain

Technovisor and Machine Vision

Unmanned Technologies

Digital Station
So far, Russian Railways is introducing and piloting individual digital solutions. But soon they will merge into the Digital Station.

Digitalization in freight transport
Russian Railways' Digital Services Make Work Easier for Business Customers


The Future Is Digital
According to the forecast of Russian Railways analysts, by 2035 the global economy will be based on the competition of digital ecosystems, the core of each will be a diversified holding. The company is ready for this scenario: it has created a powerful digital infrastructure and is developing modern technologies, including ultra-secure quantum communication networks.

Based on its IT infrastructure, Russian Railways continues digitalization, which is a strategic priority for the company for many years to come. The new digital opportunities will provide Russian Railways passengers with maximum comfort, and business customers with maximum speed, reliability and transparency of cargo transportation.

4 data processing centers and 16 road computing centers in Russian Railways IT
240,000+ automated workstations at Russian Railways
>30,000 people employed in the IT complex of Russian Railways
>7,000 km of quantum networks created by Russian Railways by 2024
74.7% level of digital literacy of Russian Railways employees (10% higher than the national average)"

Russia through the hidden eye (continuation)

http://government.ru/news/48918/ Operational meeting with Deputy Prime Ministers July 3, 2023 On the agenda: on the support of backbone enterprises of industry and trade, on the rules for granting grants for the creation and development of agro-industrial technoparks, on the course of the...

vigilantcitizenforums.com

Decree of the Government of the Russian Federation No. 3363-r dated 11/27/2021 "On approval of the Transport Strategy of the Russian Federation until 2030 with a forecast for the period up to 2035"

Russia through the hidden eye (continuation)

http://government.ru/news/48918/ Operational meeting with Deputy Prime Ministers July 3, 2023 On the agenda: on the support of backbone enterprises of industry and trade, on the rules for granting grants for the creation and development of agro-industrial technoparks, on the course of the...

vigilantcitizenforums.com

"...
2. Technological and energy risks and opportunities in the implementation of the Strategy
..
For the period from 2024 to 2030, the risks and opportunities for the emergence of both "disruptive" and breakthrough innovations are increasing, including:
..
The acceleration of the development of virtual (Virtual reality, VR), Augmented (Augmented reality, AR) and mixed reality (Mixed reality, MR) technologies will lead to a decrease in demand for passenger transportation. The pandemic of the new coronavirus infection (COVID-19) has led to a long-term transfer of the interaction of company employees to an online format, and further development of digital technologies can accelerate this trend.
...
In 2030 - 2035, the risks of the emergence of breakthrough technologies and innovations that can lead to a fundamental revision of the entire paradigm of the development of the transport industry are significantly increasing. Certain categories and parameters of risks on the long-term horizon of the Strategy implementation are formed on the basis of the analysis of scientific literature by the foresight method in relation to existing technological, economic or social trends. These include the following risks:
..
the introduction of neural interfaces-implants will lead to the transfer of smartphone functions to implants, will provide the possibility of unambiguous identification of passengers and operating personnel, integration of geo-positioning systems with implants to create personalized transport products taking into account individual mobility technologies;

the introduction of fundamentally new materials, for example, based on nanotechnology, can lead to a change in the engineering model, construction technologies;

reaching the point of technological singularity and creating a "strong" artificial intelligence.
.."

 

[Lalas]

Миссия - Золотое Сечение

Мы создаем систему ценностей, в которой каждый ребенок талантлив. Даем силу знаний, учим побеждать, сопровождаем к успеху ФОНД В ЦИФРАХИ ФАКТАХ 22 280замечательных школьников проявили свой талант на программах Фонда 18 769заинтересованных слушателей очных и дистанционных программ 3...

zsfond.ru

We create a system of values in which every child is talented. We give the power of knowledge, teach you to win, accompany you to success

The Golden Section Foundation is a regional center for identifying and supporting gifted children based on the model of the Sirius Educational Center

Education at the Foundation gives schoolchildren the opportunity to try themselves in different fields, gain new knowledge that goes beyond the school curriculum, touch big science, communicate with experts in various fields, gain vast experience, and determine their professional purpose for the future.

3 проектных дня - Золотое Сечение

Идёт регистрация на менторскую сессию для участников регионального этапа всероссийского конкурса научно-технологических проектов «Большие вызовы»

zsfond.ru

Participants of the mentoring session of the Regional Stage of the All-Russian Competition of Scientific and Technological Projects "Big Challenges" will be able to get feedback from experts, look at their project from a different angle and refine it.

We are waiting for applications until January 26 from students in grades 7-11, students of 1-2 years of secondary vocational education institutions who have not reached the age of 18 at the time of the intensive, who plan to defend their project in front of the jury and go to the Sirius Educational Center for a special shift "Big Challenges".

We are waiting for children who want to participate in the competition in one of the following areas:

"Agro-industrial and biotechnology"
"Unmanned Vehicles and Logistics Systems"
"Big Data, Artificial Intelligence, Financial Technologies and Machine Learning"
"Genetics and Biomedicine"
"Cognitive Studies"
"Space Technologies"
"New Materials"
"Nanotechnology"
"Development of the Arctic and the World Ocean"
"Advanced Manufacturing Technologies"
"Nature-Like and Neurotechnologies"
"Modern Energy"
"Smart City and Security"
"Ecology and the Study of Climate Change"

We are waiting for your application.
The winners - "Sirius".

Конкурс «Большие вызовы»

Участвуй в конкурсе научно-технологических проектов «Большие вызовы» для старшеклассников и студентов, которые занимаются научной или исследовательской деятельностью

konkurs.sochisirius.ru

Big Challenges
COMPETITION OF SCIENTIFIC AND TECHNOLOGICAL PROJECTS

Create the science of the future!

DirectionsChoose one of the 14 areas in which you will develop your project

Когнитивные исследования

Направление Всероссийского конкурса научно-технологического конкурса «Большие вызовы»

konkurs.sochisirius.ru

Cognitive Studies
Cognitive research is an interdisciplinary scientific field that opens up incredible prospects for expanding knowledge about the development of the psyche, intelligence and behavior, and most importantly, allows us to learn more about the abilities that are hidden in each of us.

Modern cognitive research includes such fields of knowledge as psychology, neurophysiology, genetics, linguistics, sociology, philosophy, artificial intelligence, and big data.

The versatility of cognitive science is explained by the complexity of the object of its research — the human psyche. To do this, researchers use psychophysiological (studying the brain and nervous system) and psychometric (studying abilities and behavior) methods. Cognitive scientists are interested in processes such as perception, attention, memory, speech, and thinking.

The most urgent tasks of cognitive science include the study of cognitive and language abilities of a person at different ages and in different conditions, the possibilities of their development, and the development of scientific foundations for effective learning.

As part of the competition, schoolchildren can develop projects, for example, to create scientifically based psychological methods, experiments to study the psychophysiological features of information perception, as well as to study the effectiveness of knowledge transfer.

Генетика и биомедицина

Направление Всероссийского конкурса научно-технологического конкурса «Большие вызовы»

konkurs.sochisirius.ru

Genetics and Biomedicine
Each of us is unique. This uniqueness in a person is laid, among other things, by his genome, which largely determines the predisposition to certain diseases, lifestyle and nutrition, and possible physical activity. That is why the average treatment often does not give the desired result – we are too individual and everyone needs a personal approach.

According to experts, the future of medicine lies in personalization, when each patient will be offered the most appropriate drug in the optimal dose for him, and in the future, an individual drug is created, the genome is edited, new non-rejectible organs are grown from the patient's cells to replace the failed ones.

On this path, researchers in the field of genomics and molecular biology, specialists in the field of tissue and bioengineering still have a lot to do. The human body is a complex system in which a huge number of processes act in concert. In this system, all of its parts and elements, including the smallest cellular organelles, are connected to each other. We do not yet have a full picture of how this system works. Therefore, the study of subtle processes at the cellular level is extremely relevant today.

No less important are the applied aspects of the problem, such as devices for early diagnosis of diseases and monitoring of biometric parameters.

Participants of the competition in this area are invited to study the biological activity of the body. An example of a school project could be the study of the concentration of various enzymes in saliva, the correlation of the results of the experiment with the physiological data of the participants obtained during the questionnaire of the participants, and the interpretation of the data obtained.

Нанотехнологии

Направление Всероссийского конкурса научно-технологического конкурса «Большие вызовы»

konkurs.sochisirius.ru

Nanotechnology
Nanotechnology is a set of chemical, physical, or "artificial" biological processes that make it possible to work in a controlled manner with nanoobjects that form various materials, devices, or technical systems.

A feature of nanotechnology is the widespread use of the processes of self-organization, self-assembly and synthesis, which in a complex organized system can lead to the formation of a set of necessary ordered structures (nanostructures) that exhibit the required practically important (functional) properties.

Nanotechnology is a comprehensive direction, without the achievements of which the development of any of the branches of the modern economy is impossible. In this regard, the problem field for research and project activities is very wide.

This year, the projects carried out within the framework of the "Nanotechnology" direction cover the problems of such industries as medicine and biotechnology, quantum technologies, ecology and modern crop production, modern energy and space, microelectronics, innovative research equipment and systems, etc.

Students go from immersion in the problems of the field itself, mastering modern research methods and principles of development in the field of high technologies to solving practical problems of the above industries. Each project has its own range of partners who work in the real sectors of the economy.

Природоподобные и нейротехнологии

Направление Всероссийского конкурса научно-технологического конкурса «Большие вызовы»

konkurs.sochisirius.ru

Nature-Like and Neurotechnologies
In recent years, scientists have increasingly turned to nature for inspiration. Their motives are clear: nature has been fine-tuning vital processes for tens of thousands of years. We can learn from it to make our lives more comfortable and safer.

Biomimetics is the science of the structure and function of biological systems as models for the design and creation of materials and mechanisms. Now, with the development of nanotechnology, it has received a powerful impetus. Bionic robots have appeared, i.e. mechanisms created on the basis of ideas spied in nature, or outwardly resembling living creatures (zoomorphs).

A neural interface, in the broad sense of the word, is a system that interacts between the human brain and a machine, which allows for the exchange of information. In today's world, unidirectional neural interfaces are used when a person sends signals and commands to a computer. But bidirectional interfaces that allow mutual interaction are still a matter of the future, albeit in the near future.

One of the examples of a project that schoolchildren can lead as part of the competition is the creation of a device for tracking the psychophysical state of a person by the movement of his pupils. For such a device, you will need: a camera, the development of a body and a method of information processing. The field of application of the installation can be professions with a high level of psychophysical stress, research centers, and medical diagnostics."

the cornerstone: "the nature–like technosphere is a part of the noosphere.."

In two words: the common point and the sought end / intermediate goal of all the Sustainable Development Goals, green programs, digitalization, technocracy and transhumanism (of which transgenderism is a part, not the other way around) including genetic programs, mass inoculation, etc. - a peek...

vigilantcitizenforums.com

 

[Lalas]

Российские инноваторы разработали концепт мобильного дронопорта

Почти 300 проектов поступило на форум «Сильные идеи для нового времени» по направлению «Технологическое развитие». Среди предложений – решения по созданию…

ru-bezh.ru

Russian innovators have developed a concept for a mobile drone port

12.01.2023
Almost 300 projects were submitted to the forum "Strong Ideas for a New Time" in the field of "Technological Development". Among the proposals are solutions for the creation of refueling stations-airfields for drones, mobile drone ports and firefighting UAVs, according to the ASI website.

One of the applications was submitted by Alexander Prutov from the Chelyabinsk region. He proposed to create a "Dronoport Ural". The project involves the creation of such drone ports based on Ural and KamAZ vehicles, as well as equipment from the BRICS countries. The vehicle is transformed into a mobile ground control point for UAVs, and at the same time into a charging and repair station, as well as a mini-airport for their base. The solution can be useful for the agricultural and oil and gas industries, which use drones.

The goal of the project is to use drone ports to receive information from remote facilities, create field work bases, integrate various types of UAVs into the work of organizations, and form logistics hubs for passenger and cargo drones. This solution can be used in different climatic zones.

Генеральный директор АСИ Светлана Чупшева: удовлетворенность граждан оказанием социальных услуг растет

Новости Агентства стратегических инициатив

asi.ru

ASI Director General Svetlana Chupsheva: citizens' satisfaction with the provision of social services is growing
January 12, 2024

Умер один из создателей вакцины "Спутник V" Борис Народицкий

Ему было 82 года

nauka.tass.ru

11 January, 2023
One of the creators of the Sputnik V vaccine, Boris Naroditsky, has died
He was 82 years old

Россия и Индия развивают сотрудничество в сфере стандартизации ИИ

Россия и Индия совместно разрабатывают проект "Белой книги" оценки соответствия технологий искусственного интеллекта, в которой будут отражены согласованные двумя государствами цели и задачи оценки соответствия технологий искусственного интеллекта (ИИ), существующие на российском и индийском...

www.comnews.ru

Russia and India develop cooperation in the field of AI standardization

10.01.2024

Russia and India are jointly developing a draft White Paper on Conformity Assessment of Artificial Intelligence Technologies, which will reflect the goals and objectives of conformity assessment of artificial intelligence (AI) technologies agreed upon by the two states, existing in the Russian and Indian markets AI solutions in pilot industries; the status of international and national standardization documents in relation to pilot industries; approaches to the ethical regulation of AI agreed by the two countries. This was reported by the press service of Rosstandart.

The use of artificial intelligence technologies in healthcare and agriculture was selected as pilot projects.

The project is being implemented within the framework of the memorandum of cooperation signed in the fall of 2023 between the Chamber for India-Russia Technology Cooperation, the Russian Technical Committee for Standardization No. 164 "Artificial Intelligence" (TC 164) and the non-profit partnership of software developers "Russoft". The main goal of cooperation is the creation of a unified system for assessing the compliance of artificial intelligence technologies. Within the framework of the pilot project, approaches to assessing the compliance of AI in agriculture and healthcare will be developed that are acceptable for the two countries, taking into account the analysis of AI applications in healthcare and agriculture in Russia and India; development of quality assessment metrics for AI technologies participating in the pilot experiment and requirements for the quality of AI applied technologies, including in comparison with the quality of a human operator. The pilot project will also result in unified standardization documents in Russia and India, establishing requirements for testing certain applied AI technologies in the field of healthcare and agriculture.
...
The first results of Russian-Indian cooperation in the field of standardization and conformity assessment of artificial intelligence technologies will be presented at the summit of the heads of national standardization bodies of the BRICS member states, which will be held in the summer of 2024 under the chairmanship of the Russian Federation.

Нейросеть научили распознавать подозрительные транзакции | Новости науки

Главные новости российской науки на официальном сайте Десятилетия науки и технологий в России

xn--80aa3ak5a.xn--p1ai

NEURAL NETWORK TAUGHT TO RECOGNIZE SUSPICIOUS TRANSACTIONS

JANUARY 9, 2024
Scientists from South Ural State University have taught artificial intelligence to recognize suspicious bank transactions using gradient boosting. The algorithm can be used both in the day-to-day work of the security service of banks and in the control of "digital currency".

В РФ разработали подход, помогающий нейросетям лучше распознавать юмор

Ученые изучили способность распознавать юмор как у относительно простых нейросетей на базе алгоритма RoBERTa, так и у передовых больших языковых моделей, таких как ChatGPT и Flan-UL2

nauka.tass.ru

The Russian Federation has developed an approach that helps neural networks better recognize humor

The scientists studied the ability to recognize humor in both relatively simple neural networks based on the RoBERTa algorithm and advanced large language models such as ChatGPT and Flan-UL2

TASS, January 11, 2023. Russian researchers have developed an approach that makes it possible to select such datasets for training language neural networks, which will help these AI systems learn to more accurately recognize humor and distinguish it from other forms of content. This was reported on Thursday by the press service of the Higher School of Economics.

"Scientists have proposed a change in the approach to teaching and evaluating models of humor recognition. We need new datasets that are more diverse and closer to ordinary conversations and natural communication. Large language models trained on huge data sets of different types are on average good at recognizing humor, and the scientists suggest that it is the diversity of the data they learned from.

This is the conclusion reached by a group of Russian researchers led by Pavel Braslavsky, Associate Professor at the Faculty of Computer Science at the Higher School of Economics, while studying how existing neural network algorithms cope with the recognition of different forms of humor. In the course of these experiments, the researchers assessed how different approaches to training language models and the data sets used in them affect the neural network's ability to distinguish humor from other forms of content.

The researchers studied the ability to recognize humor in both relatively simple neural networks based on the RoBERTa algorithm and advanced large language models such as ChatGPT and Flan-UL2. In addition to standardized tests for humor, the scientists tested whether neural networks could detect humor or its absence in dialogues from the works of Lewis Carroll, Charles Dickens, Jerome K. Jerome, several TV series, as well as in ironic messages from social networks.

A New Approach to Neural Network Training
"We showed different models Dickens' Antiquities Shop, which is a very sad story, and asked them to evaluate what was happening. It turned out that some models thought that all dialogues from 19th-century literature were funny. And even more: everything that is too different from the news of the 21st century is perceived by them as humor," explained one of the authors of the study, Alexander Baranov, whose words are quoted by the press service of the Higher School of Economics.

This problem, as the scientists note, was more typical for algorithms trained on monotonous and voluminous data sets. In contrast, neural networks trained on sets of small parts of different collections of texts were much more successful in recognizing humor. According to the researchers, this suggests the need to increase the diversity of humor examples when training language neural networks.

In particular, this is supported by the fact that ChatGPT and Flan-UL2, trained on very large and diverse sets of texts, on average, were noticeably better at recognizing humor than highly specialized neural networks based on the RoBERTa algorithm. Understanding this, scientists hope, will significantly improve the quality of voice assistants and other AI systems, which often encounter jokes and other manifestations of humor.

"We Are on Track towards Personalised Medicine"

The International Laboratory of Bioinformatics of the HSE Faculty of Computer Science and its partners in the Genetics of Cardiovascular Diseases Consortium are working on a new project titled ‘From Sequencing to the Development of a Cardiogenetic Test’ (in Russian). The Head of the...

www.hse.ru

10 January 2024
'We Are on Track towards Personalised Medicine'

 

[Lalas]

В России начнут испытывать имплант-восстановитель функций ампутированной конечности

Новый протез отличается высокой прочностью, а значит, не потребует частой замены, сообщил директор по развитию Уральского НОЦ Игорь Манжуров

nauka.tass.ru

Russia through the hidden eye

https://rigf.ru/en/ The 13th Russian Internet Governance Forum April 6–7 2023 SUPPORTED BY Ministry of Digital Development, Communications and Mass Media of the Russian Federation ORGANIZERS Russian domains .RU and domain space expertise and https://cgitc.ru/en/ SUSTAINABLE FUTURE OF GLOBAL...

vigilantcitizenforums.com

 

[Lalas]

About

VCIOM (Russian Public Opinion Research Center) is the first and the largest polling firm in the Former Soviet Union (FSU). Established in 1987 it is most widely known polling company in Russia. VCIOM is especially known for its weekly nationwide representative opinion polls (Omnibus type of survey conducted face to face), daily telephone surveys and regular online studies. In 2017, the company launched its daily telephone-based survey project called ‘Sputnik’ (1600 respondents per day) and today VCIOM is the only company in the post-Soviet space which measures public opinion on the current issues in real-time mode (the data is collected every day).

VCIOM has membership in global and regional professional communities such as ESOMAR and OIROM (Russian Association for Market and Opinion Research) and owns 80% of the Mediascope Company’s stock (Mediascope is the leading audience research company in Russia). VCIOM is a cofounder of ‘Eurasian Monitor’ International Research Agency and of the Independent Institute of Social Policy (NISP) – due to this VCIOM is capable of conducting regular studies throughout all FSU countries (former Soviet republics).
...
We are headquartered in Moscow, have offices across the whole country, as well as firm ties with the polling centers around the world (from Kazakhstan and Germany to Japan and China). Over three decades our team that includes the best professionals in the areas of sociology, marketing, psychology, political science and finance has provided its expertise to over 2000 clients, representing both public and private sectors.

Press release

NATIONAL UNITY IN 2023
02.11.2023

MOSCOW, 2 November 2023. Russian Public Opinion Research Center (VCIOM) presents the findings of a survey devoted to National Unity Day.

An important day in national history

Three-quarters of Russians recognize the importance of celebrating National Unity Day (75%); 39% report about it with full confidence, which is an all-time high. Four years ago, during the COVID-19 restrictions, this holiday was far less important: only a quarter of respondents considered it a significant holiday (24% in 2019). However, the following year (2022) the percentage approached the pre-pandemic level of 32%.
...

https://sociodigger.ru/

About the publication
Since 2020, VTsIOM has been publishing a new monthly expert and analytical publication, SocioDigger, dedicated to the study of the main changes and trends in the life of Russian society. Its pages combine data and analytics, figures and meanings, author's expert positions and empirical cross-sections of public life. Our publication brings together materials from discussions at the VCIOM event platform "Professional Conversation" and meetings of the Scientific Council of the Russian Public Opinion Research Center, as well as reports prepared jointly with leading Russian analytical centers. The publication provides an opportunity to get acquainted with the most extensive database of polling data of the Russian Public Opinion Research Center (VTsIOM), both the most recent and with "immersion" in the more than 30-year history of research. All issues are prepared with the participation of experts – researchers and practitioners, representatives of government bodies, business, the media and NGOs.

https://sociodigger.ru/articles/articles-page/doroga-v-budushchee-kak-rabotat-s-rastushchei-neopredelennostju

EXTENDED COMMENTARY

30.10.2021

The Road to the Future: How to Deal with Growing Uncertainty

Luksha Pavel Olegovich
Founder of the Global Education Futures initiative, expert at the Skolkovo Center for Education Transformation

The increasing complexity of the world is the main challenge

We are at a very interesting stage of civilization. The complexity of the world and its interconnectedness are growing. For example, if we compare a medieval, early industrial city and a modern one—say, Moscow of the 16th century, the 19th century, and the current one—it is obvious that the modern city is richer in terms of the variety of activities and is much more complex. In short intervals, this complication is less obvious, and in longer intervals it is very pronounced. And the more complex the system, the more critical its long-term orientation is. It should not act reactively, but be able to turn towards new goals.

And today we are not just continuing the peace that has been with us over the past centuries, but we are at the point of a kind of reassembly. There is an active rethinking of how the economic and management model will work in general. This, of course, is related to digitalization, as there is a change in the leading communication environment, the learning environment, and the creative environment. But it's also that we're facing a huge number of challenges on a global scale, and cultures are starting to change. A whole layer of new values and meanings is emerging: supranational, planetary, and universal. In fact, a single humanity is being born, and this is a common process that is taking place all over the planet.

From the point of view of people who do not see and do not feel this process, the uncertainty of their lives increases. Previously, it was possible, as in Japanese corporations, to go to a company and understand that your life is predetermined, to have guaranteed employment throughout your life and clear career growth, an understanding of when and what kind of car you can buy, a house, and so on. Now the entire industrial world, all developed countries have abandoned this model, even the Japanese (in 2019, this was even officially announced by the Japan Business Association), organizations and states around the world are beginning to play "short". In many ways, citizens are simply hostages to this process – they may be happy to set goals for themselves for half a lifetime, but they are constantly told that it is not clear what the economy of tomorrow will be like, and maybe your job will disappear altogether. People are forced to abandon the long-term contour not because they are short-sighted, but because life does not provide them with these guidelines.

A contradiction has emerged: on the one hand, there is the need for long-term goal-setting on a global scale, and on the other hand, there is the logic of reassembly, which forces people to live in conditions of growing uncertainty and complexity of the world. The old method of long-term goal-setting has broken down, and the new one is still in the process of being developed.

Two Answers to the Main Question

In conditions of increasing turbulence, certainty can be "betrayed", firstly, by traditional structures, such as religion and tribal systems. They have held their bearings since ancient times – once upon a time, hunger, cold, and plague were common circumstances of life. Tribal and religious communities provided support, protection, and values. Then the process of their degradation began, which is associated with the spread of the current civilizational way of life on the planet. Yuval Harari (and others) writes that in industrial society, the formats of collective existence have been destroyed in the interests of nation-states and market structures. People began to be told that he was a person, that he could do everything on his own. This freed up a huge personal resource, but at the same time made the individual defenseless against the forces of the market and state violence. And where the ancient forms of collective existence were not so badly destroyed, it is easier for a person to live with this turbulent reality, he really has a foothold. It is another matter whether it responds to the challenges of the future, whether they are ready for the emergence of, for example, artificial intelligence, infodemics and other phenomena of the 21st century. Archaic systems are a way to solve the problem of uncertainty, but they do not help to prepare for the future, and this is their main problem. I call this the dead-end of traditionalism: tradition gives guidelines and an understanding of why a person should live, but says nothing about how to adapt if the situation changes even more. And then, suddenly, traditional societies find themselves in the position of losers. The most that the systems that inherit traditionalism can do at each next step is to buy the products that a growing complex civilization produces. They may have advanced smartphones, jeeps, and weapons of the latest system, but they can't build them. And in the end, you still have to change, as we see, for example, in the situation of traditional Arab societies.
....."
~~~~
This does not stop there, Luksha continues article, but the great forum software does not allow me to publish the extension because: "Oops! We ran into some problems. Please try again later."

Not that anyone cares (or that someone should be interested), just to I complain, complain, and that's it.

"Freedom of speech has been banned. Muted..."


I don't know what those banned code words are, since there is nothing special in the comment sequel, nothing more than things I've already posted. Mystery. I noted it, satisfied myself with the need to moan, and I continue.

... This actually kills wonderfully the desire to prepare some long posts and any posts in general. With this earring on the ear (and this is not the first time, so there are more earrings), every time you decide to start writing a post, you expect that in the end, when you decide to publish it, you will get: "Oops! We ran into some problems. Please try again later." And when we put into account that in fact almost no one is interested in the things I publish here, a great pretext is formed to I stop doing it. It would be good for me and irrelevant for everyone else. It can happen, it sounds good. In the future. For now, I'm still dumb and stubborn.
~~~~

More about Luksha's ideas and plans for the future, and more, and more, and more.

 

[Lalas]

The Dalai Lama Supports 2045’s Avatar Project

The 2045 initiative has received the blessing and support from the Dalai Lama, as it prepares to announce the second Global Future 2045 Congress, being held in New York, June, 2013. Congress will gather world leading scientists and public figures to discuss how Avatar technologies can drive...

2045.com

Interfaith dialog
04.05.2012

The 2045 initiative has received the blessing and support from the Dalai Lama, as it prepares to announce the second Global Future 2045 Congress, being held in New York, June, 2013.

Dmitry Itskov, founder of 2045, met His Holiness Tenzin Gyatso, the 14th Dalai Lama, in his residence in Dharamsala, a small mountain town in northern India.

They discussed the three major steps of 2045 Avatar Project. First, the creation of a human-like robot dubbed “Avatar A,” and a state-of-the-art brain-computer interface system to link the mind with it. Next, it be created a life support system for the human brain, which connects to the “Avatar A,” turning into “Avatar B.” The third step, named “Avatar C”, is developing an artificial brain in which to transfer one’s individual consciousness with the goal of achieving cybernetic immortality.

Creating the “Avatar C” through developing an artificial brain and understanding the nature of human consciousness, says the Dalai Lama, could be attainable, and would be a great benefit to future development of science.

“In the last few years, scientists now begin to show an interest about consciousness, as well as brain specialists, neuroscientists, who also begin to show interest about consciousness or mind. I feel that over the next decades modern science will become more complete,” said the Dalai Lama. “So up to now the matter side of science has been highly technical, highly advanced, but the mind side has not been adequate. This project, definitely, is helpful to get more knowledge.”

Several months ago, DARPA – the Pentagon’s research arm – announced their own plans on creating a militarized avatar project, serving as a soldiers surrogate on the battlefield.

“My project has very different, humanitarian goals – it involves technologies that could mark a transition for humanity, with endless benefits in the future. But already in the next few years, we will be able to enhance the life of those who are disabled, radically improving their living standards. This is just the beginning. It’s my goal to ensure it is affordable and accessible for all people - not just for the elite and the military,” said Itskov.

The Dalai Lama also agreed that it is crucial to discuss the ethics behind these types of progressive technologies. “We should carry out these experiments with a full sense of responsibility and respect for life that will only benefit humanity, benefit others.”

Itskov has been reaching out to spiritual leaders to start a dialogue about how they could reach harmonious integration with scientists. “It’s important to establish a bridge between scientists and spiritual leaders for a successful transition to a new phase for humanity,” he said.

The 2045 initiative held its first Global Future 2045 Congress in Moscow, in February 2012. There, over 50 world-leading physicists, biologists, anthropologists, sociologists, psychologists, and philosophers met seeking to develop a strategy for further development of the humankind. The initiative’s goal is to create a network with the world’s leading scientists who are focused on the development of cybernetic technology with the ultimate goal of transferring human’s individual consciousness to an artificial carrier. The network will act as an investment hub, contributing to various projects around the world.

 

[Lalas]

Глобальное будущее 2045. Конвергентные технологии (НБИКС) и трансгуманистическая эволюция

Книга посвящена осмыслению философских и теоретических вопросов настоящего и будущего нашей цивилизации. В ней охватывается широкий круг проблем, котор...

scientifically.info

GLOBAL FUTURE 2045. CONVERGENT TECHNOLOGIES (NBICS) AND TRANSHUMANIST EVOLUTION

2013.12.14
The book is devoted to the comprehension of philosophical and theoretical issues of the present and future of our civilization. It covers a wide range of problems, which is defined by three main themes: 1) the global future, the singular threshold of the middle of the twenty-first century, scenarios for the development of civilization; 2) convergent megatechnologies, their role in the transformation of man and society; 3) issues of transhumanist evolution related to the tasks and projects of the Strategic Public Movement "Russia 2045", analysis of the most common concepts of transhumanism. The authors focus on the problems of the anthropological crisis, the ways to overcome it and the transition of the earthly civilization to a qualitatively new stage of development. The book was prepared by the Scientific Council of the Public Movement "Russia 2045".

The goals and projects of the Strategic Public Movement "Russia 2045" related to the scenarios of the future of our civilization, transhumanist evolution, transformations of human corporeality and society, radical extension of life (up to cybernetic immortality) cause various assessments in the scientific community and serve as the subject of lively discussions. It is clear to everyone, however, that the acute raising of questions about ways to overcome the anthropological crisis, to get our civilization out of the consumer impasse, to change the disastrous trajectory of its development is extremely relevant, and urgently requires the unification of social forces, the concentration of creative efforts to comprehend them and to create means for their solution.

This is the main task of the Public Movement "Russia 2045", which already has more than 20,000 supporters; Among them are prominent scientists, philosophers, and cultural figures. It strives to become a catalyst for a powerful all-Russian and then international movement capable of creating spiritual and material resources, real forces to confront the global threats of the not so distant future.

In February 2012, the organizers of the Movement, headed by its founder Dmitry Itskov, held the First International Congress "Global Future 2045" in Moscow, which was attended by a total of about 1,500 people, including prominent scientists from the United States, Western Europe, Australia, and Canada. Preparations are under way for a second international congress on the same subject, to be held in June 2013 in New York.

The goals and projects of the Russia 2045 Movement were discussed at a number of conferences, scientific seminars, round tables, and at a meeting of the Scientific Council of the Russian Academy of Sciences on Artificial Intelligence Methodology. Despite the criticisms, the participants of the discussion unanimously emphasized the exceptional importance of the issues and tasks set by the Movement, the high social need for their thorough development and solution. Given the scale and complexity of these issues and tasks, the Scientific Council of the Russia 2045 Public Movement has recently been established. It included V.I. Arshinov, V.G. Gorokhov, S.V. Krichevsky (Doctor of Philosophy, Candidate of Technical Sciences, test cosmonaut), V.E. Lepsky, V.S. Stepin (Academician of the Russian Academy of Sciences), B.G. Yudin (Corresponding Member of the Russian Academy of Sciences), other well-known philosophers, as well as such prominent scientists as V.L. Dunin-Barkovsky, A.Y. Kaplan, A.P. Nazaretyan, A.D. Panov, V.F. Petrenko (Corresponding Member of the Russian Academy of Sciences), V.G. Redko, S.F. Sergeev, A.A. Frolov and others. Soon, the composition of the Council will be expanded by attracting major foreign scientists to it.

The Council is called upon to develop the theoretical foundations of the tasks set by the Movement, to contribute to the solution of interdisciplinary and transdisciplinary problems put forward by the convergent development of NBICS (nano-, bio-, informational, cognitive, social technologies and relevant fields of scientific knowledge), on which, mainly, the future of our civilization now depends, as well as to promote comprehension and in-depth analysis of the socio-humanitarian component of the NBICS, since it belongs to it A leading role in the system of development of convergent technologies and solving the problems of the development of the Earth's civilization.

The initial product of the Council's work is the book that you, the reader, hold in your hands. It represents the first step in the creation of a sound scientific, theoretical, methodological and philosophical basis for the Movement. It covers a wide range of issues, which (as indicated in the title of the book) are linked by three main themes:

1) the global future, the singular boundary of the middle of the century, scenarios for the development of civilization;
2) convergent technologies, their role in the transformation of people and society;
3) issues of transhumanist evolution, analysis and evaluation of views developed in this regard, including a critical discussion of a number of concepts of transhumanism.

Of course, all three topics are interdependent, closely intertwined with each other and cannot be rigidly delineated. Therefore, the allocation of three sections of the book (according to the above-mentioned topics) is to a certain extent arbitrary. However, it still makes it possible to focus on the main aspects of the problems of the Russia 2045 Movement.

Nowadays, the world literature pays close attention to the theoretical comprehension of the projects of the future, because it is to a large extent in the hands of man, depends on our creative activity, on the consolidation of the activities of advanced social forces to achieve the vital goals of humanity. We are faced with the task of choosing a strategic direction for the development of our civilization and creating "tools for managing the future." This is the ultimate goal set by the Movement's Russia 2045 technoproject. It is designed to mobilize and elevate the creative energy and fortitude of scientific researchers and cultural figures. A lofty goal capable of uniting many people is desperately needed by Russia now. On the way to solving the super-task, there is no doubt that many private, but extremely urgent and vital tasks for our country and for humanity can be successfully solved. In this respect, history has more than once demonstrated the great role of a super-task that corresponded to the spirit of the times.

The authors are clearly aware of the extreme complexity and debatability of many of the issues raised and discussed in the book. Among them, there are some discrepancies regarding the assessment of feasibility, timing and methods of solving individual problems, interpretations of the process of transhumanist evolution and the attitude to the ideas of Western representatives of transhumanism.

We are open to criticism, to intellectual communication with our opponents, to creative discussions. But we believe in our just cause. And we hope that many opponents will still be able to contribute to the projects of the Russia 2045 Strategic Public Movement and, most importantly, to their implementation.

The electronic version of the book is provided for reference only. If you like the content of the book, buy it by supporting the author!

D.I. Dubrovsky

Глобальное будущее 2045 - Конвергентные технологии и трансгуманистическая эволюция

Цели и проекты Стратегического общественного движения «Россия 2045», связанные со сценариями будущего нашей цивилизации, трансгуманистической эволюцией, преобразованиями человеческой телесности и социума.

esxatos.com

The goals and projects of the Strategic Public Movement "Russia 2045" related to the scenarios of the future of our civilization, transhumanist evolution, transformations of human corporeality and society, radical extension of life (up to cybernetic immortality) cause various assessments in the scientific community and serve as the subject of lively discussions. It is clear to everyone, however, that the acute raising of questions about ways to overcome the anthropological crisis, to get our civilization out of the consumer impasse, to change the disastrous trajectory of its development is extremely relevant, and urgently requires the unification of social forces, the concentration of creative efforts to comprehend them and to create means for their solution.

This is the main task of the Public Movement "Russia 2045", which already has more than 20,000 supporters; Among them are prominent scientists, philosophers, and cultural figures. It strives to become a catalyst for a powerful all-Russian and then international movement capable of creating spiritual and material resources, real forces to confront the global threats of the not so distant future.

In February 2012, the organizers of the Movement, headed by its founder Dmitry Itskov, held the First International Congress "Global Future 2045" in Moscow, which was attended by a total of about 1,500 people, including prominent scientists from the United States, Western Europe, Australia, and Canada. Preparations are under way for a second international congress on the same subject, to be held in June 2013 in New York.

Global Future 2045. Convergent Technologies (NBICS) and Transhumanist Evolution
Edited by Prof. D.I. Dubrovsky

Content:

I. GLOBAL FUTURE
V. S. Stepin - A Turning Point in Civilizational Development. Points of growth of new values
A. P. Nazaretyan - Worldview Perspective of Planetary Civilization
E.G. Grebenshchikova - Foresight Technologies: From Predictions to Designing the Future
S. V. Krichevsky - The Settlement of Mankind Beyond the Earth: Problems and Prospects
V. E. Lepskii - The Problem of Assembling Development Subjects in the Context of the Evolution of Technological Modes
V.G. Gorokhov, M. Decker - Technological Risks as a Social Problem in the Development and Implementation of Intelligent Autonomous Robots

II. CONVERGED TECHNOLOGIES
V.I. Arshinov - Convergent Technologies (NBICS) and Transhumanist Transformations in the Context of the Paradigm of Complexity
V.V. Chekletsov - Hybrid Reality. NBICS as a Human-Machine Interface
D.I. Dubrovsky - The Problem of "Consciousness and Brain": Theoretical and Methodological Issues (in Connection with the Tasks of NBICS Convergence)
V. L. Dunin-Barkovsky - On the Question of the Reverse Construction of the Brain
S. F. Sergeev - Science and Technology of the XXI Century. Communications and NBICS Convergence
Y.M. Serdyukov - Informational Integrity of a Person as a Prerequisite for the Creation of His Cybernetic Avatar

III. TRANSHUMANIST EVOLUTION
Nesterov - The Problem of Man in the Light of the Ideology of Evolutionary Transhumanism
I.V. Dyomin - Humanism and Transhumanism: The Problem of Correlation
P.N. Baryshnikov - Typology of Immortality in the Theoretical Field of French Transhumanism
R.R. Belyaletdinov - Man of the Transhumanist Period: New Concepts of Man in the Age of Biotechnology
D.I. Dubrovsky - Human Nature, Anthropological Crisis and Cybernetic Immortality
V. F. Petrenko - Consciousness and the Problem of Contact with Extraterrestrial Civilizations

Application. Valentin Turchin and Cliff Joslin - Cybernetic Manifesto

НАУЧНЫЙ СОВЕТ ОБЩЕСТВЕННОГО ДВИЖЕНИЯ «РОССИЯ 2045»

В Научный совет Движения "Россия 2045" вошли видные российские ученые, в том числе академики РАН, доктора и кандидаты наук, профессоры вузов. Председателем Научного совета избран Давид Израилевич Дубровский, сопредседателями стали Владимир Иванович Аршинов, Виталий Львович Дунин-Барковский и...

www.2045.ru

http://2045.ru/pdf/globalfuture2045.pdf

~
Draft Decree of the President of the Russian Federation "On the Strategy for the development of nature-like (convergent) technologies" (June 14, 2022), full text:

the cornerstone: "the nature–like technosphere is a part of the noosphere.."

In two words: the common point and the sought end / intermediate goal of all the Sustainable Development Goals, green programs, digitalization, technocracy and transhumanism (of which transgenderism is a part, not the other way around) including genetic programs, mass inoculation, etc. - a peek...

vigilantcitizenforums.com

"Convergence of sciences and technologies – integration, fusion of sciences and technologies, their methods and approaches, allowing to obtain results that are fundamentally unattainable within each of the converging sciences and/or technologies separately. Currently, convergent sciences and technologies include a group of NBICS technologies (nano-, bio-, information, cognitive, socio-humanitarian technologies), but the list is open and can be expanded later.

Nature–like technologies are technologies that reproduce systems and processes of wildlife in the form of technical systems and technological processes integrated into the natural resource turnover. Convergent NBICS technologies are tools for creating nature-like technologies."

the cornerstone: "the nature–like technosphere is a part of the noosphere.."

In two words: the common point and the sought end / intermediate goal of all the Sustainable Development Goals, green programs, digitalization, technocracy and transhumanism (of which transgenderism is a part, not the other way around) including genetic programs, mass inoculation, etc. - a peek...

vigilantcitizenforums.com

"...
Research and development in the field of NBICS convergence as a tool for creating nature-like technologies is actively conducted in a number of foreign countries, primarily in the USA.

In particular, in the USA there is a program of the National Science Foundation and the US Department of Commerce called NBIC – "Nanotechnology, Biotechnology, Information technology and Cognitive science". In other countries, similar convergent programs are known by the acronyms GRAIN (Genetics, Robotics, Artificial Intelligence and Nanotechnology) and BANG (Bits, Atoms, Neurons, Genes). These programs are largely focused on the development of human resources. Thus, the NBIC program of the USA is called "Converging Technologies for Improving Human Perfomance", and the NBIC program of the European Union is "Converging Technologies for the European Knowledge Society) (CTEKS)."

 

[Lalas]

Академик РАН назвал гармонию ИИ и естественного интеллекта залогом будущего

Научный руководитель Национального центра физики и математики Александр Сергеев считает, что другого будущего, кроме равновесного взаимодействия природного и искусственного интеллекта, "нам точно не дано"

nauka.tass.ru

Academician of the Russian Academy of Sciences called the harmony of AI and natural intelligence the key to the future

Alexander Sergeev, scientific director of the National Center for Physics and Mathematics, believes that "we definitely have no other future" than the equilibrium interaction of natural and artificial intelligence

SAROV /Nizhny Novgorod region/, November 20, 2023. A harmonious interaction of natural and artificial intelligence needs to be built in the future, and the current young generation will take an active part in this. This opinion was expressed by the scientific director of the National Center for Physics and Mathematics, Academician (NCFM) of the Russian Academy of Sciences Alexander Sergeev.

"A lot of things can be seen in our brains that can be implemented in an artificial intelligence system. This is being done now, this is a very interesting modern direction. <... >We can say that our future is in the properly built interaction of natural intelligence with artificial intelligence, this future will come very quickly," Sergeyev said during the opening ceremony of the first All-Russian School on Artificial Intelligence and Big Data in Sarov.

He noted that the current young generation will take an active part in this. According to Sergeev, the NCFM is already paying great attention to artificial intelligence, this direction in the center is the main one.

"How to develop artificial intelligence and how to properly arrange its interaction with natural intelligence so that both develop harmoniously in interaction with each other. We definitely have no other future," the academician added.

The National Center for Physics and Mathematics in Sarov is being built on behalf of Russian President Vladimir Putin. This is the flagship project of the Decade of Science and Technology. A complex of research buildings, advanced laboratories and facilities of the "middision" and "megascience" class is being built on the territory of the NCFM to obtain world-class scientific results, train highly qualified scientists, educate scientific and technological leaders, strengthen the human resources of Rosatom enterprises and key scientific organizations of the Russian Federation.

Глава РАН анонсировал появление системы рейтингования научных институтов к середине года

Рейтинг нужен для того, чтобы коллективы и руководители институтов понимали, какое место занимают их научные центры, сообщил Геннадий Красников

nauka.tass.ru

The head of the Russian Academy of Sciences announced the emergence of a rating system for scientific institutes by the middle of the year

The rating is needed for the teams and heads of institutes to understand the place of their research centers, Gennady Krasnikov said

MOSCOW, January 15, 2023. Work on the rating system for research institutes in the Russian Federation will be completed by the middle of the year, President of the Russian Academy of Sciences (RAS) Gennady Krasnikov told a TASS correspondent.

In December, at the general meeting of the Russian Academy of Sciences, the head of the Ministry of Education and Science of the Russian Federation, Valery Falkov, and the president of the academy, Krasnikov, announced the prospect of abolishing the division of research institutes into three categories from 2024. Categorization should be replaced by rating, but it will not affect the financing of institutions, the head of the Russian Academy of Sciences said at the time.

"We will prepare it closer to the summer. <... > [The rating is needed] so that the teams and heads of institutes understand what [their research centers] occupy and so that there is motivation to move forward - to increase the potential in terms of research and achieve scientific results," Krasnikov said, answering a question about the expected timing of the development of the assessment system.

The division of academic institutions into three categories has existed since the days of the USSR, and the financing and economic situation of a research center depend on this. The last time the categories were assigned was in 2018. According to Krasnikov, such a classification, in particular, led to the fact that the institutes of the second and third categories "were actually deprived of development," since they could not take part in the competition that allows them to update scientific equipment.

"Now any institute can apply and take part in this competition," said the President of the Russian Academy of Sciences.

Более четверти опрошенных россиян заявили, что могут не заходить в интернет максимум день

Еще 46% респондентов утверждают, что смогут легко обойтись без выхода в онлайн неограниченное количество времени, свидетельствуют итоги опроса медиахолдинга Rambler&Co

tass.ru

January 15, 2023
More than a quarter of Russians surveyed said that they may not go online for a maximum of a day
..
"Slightly more than half (53%) of the surveyed Russians said that they could not imagine their life without the use of the Internet. 47% are not against breaks and "detox" from gadgets. At the same time, 46% claim that they can easily do without going online for an unlimited amount of time. For 27%, the maximum abstinence is one day," the study said.

At the same time, 14% of respondents also admit that they cannot do without using the Internet for more than a few hours, 9% are able to live without the global network for a week, and 4% said that after an hour they feel anxious.

В России разработали бионический протез уха, максимально приближенный к реальному

Специалисты смогли с помощью технологий 3D-печати повторить в конструкции искусственного уха рельеф реального органа и сделать так, чтобы каркас устройства включал в себя необходимые для работы протеза электронные компоненты

nauka.tass.ru

15 January, 2023
In Russia, a bionic ear prosthesis has been developed, which is as close as possible to the real one

With the help of 3D printing technologies, specialists were able to replicate the relief of a real organ in the design of the artificial ear and make sure that the frame of the device included the electronic components necessary for the operation of the prosthesis

Ученые МГУ научились управлять адгезией бактерий к имплантатам

Биоинженеры и биохимики биологического факультета МГУ совместно с химиками и физиками Томского политехнического университета разработали пьезоактивные биоматериалы, адгезия бактерий к которым управляется внешним магнитным полем.

www.msu.ru

12/01/24
MSU Scientists Have Learned to Control the Adhesion of Bacteria to Implants

Bioengineers and biochemists of the Faculty of Biology of Moscow State University, together with chemists and physicists from Tomsk Polytechnic University, have developed piezoactive biomaterials, the adhesion of bacteria to which is controlled by an external magnetic field. The study is published in the International Journal of Molecular Sciences.

Adhesion of Escherichia coli and Lactobacillus fermentum to Films and Electrospun Fibrous Scaffolds from Composites of Poly(3-hydroxybutyrate) with Magnetic Nanoparticles in a Low-Frequency Magnetic Field

The ability of materials to adhere bacteria on their surface is one of the most important aspects of their development and application in bioengineering. In this work, the effect of the properties of films and electrospun scaffolds made of composite materials based on biosynthetic...

www.mdpi.com

The connective tissues of the human body, such as bone, cartilage, tendon, skin, and ligament tissues, have piezoelectric properties. This is the ability of some materials to generate an electric charge on their surface in response to mechanical deformation. The resulting electric field, for example, during rhythmic mechanical stress on bones, cartilage and ligaments during walking, regulates the normal functioning of the cells of these tissues, including the regeneration of tissues when they are damaged. Surprisingly, some polymers of bacterial origin, such as poly-3-hydroxybutyrate and its copolymers, also have piezoelectric properties. And while studies of the effect of the piezoelectric effect on animal cells are being conducted, its role for bacteria remains practically unstudied. In addition, these bacterial polymers are highly biocompatible and biodegradable, making them highly promising for the design of tissue-engineered scaffolds and implants for regenerative medicine.

In this regard, the scientists used poly-3-hydroxybutyrate to create a new artificial biomaterial with a complex imitation of not only the structure and physicochemical properties of connective tissue, but also its piezoelectric properties. First of all, poly-3-hydroxybutyrate with a given chemical structure was obtained by controlled bacterial biosynthesis. Then, to mimic the structure of connective tissue, which consists of a weave of polymer fibers, an electroforming method was used to create fibrous scaffolds from poly-3-hydroxybout. To multiply the piezoelectric effect, the scientists added magnetically active nanomaterials – magnetite nanoparticles and their complexes with graphene oxide – to the polymer base of poly-3-hydroxybutyrate, which made it possible to turn on and off the generation of an electric field on the surface of such a material using an external alternating magnetic field. For the same purpose, they designed a unique installation for the generation of an external magnetic field of low frequency (about 1 Hz).

Given that the biomaterial under study is of bacterial origin, its ability to control the behavior of living cells was studied on bacteria when exposed to an external magnetic field.

"To identify the ability of our piezoactive biomaterial to control cell behavior, we selected 2 different species of bacteria: Gram-negative Escherichia coli and Gram-positive Lactobacillus fermentum. We saw that the external magnetic field caused a pronounced manifestation of the piezoelectric effect in the polymer biomaterial with magnetic nanoparticles and its biological effect on cells, which was expressed in a decrease in adhesion to the surface of lactobacillus scaffolds by almost 2 times. At the same time, the manifestation of the piezoelectric effect in relation to E. coli was much less pronounced, but a pronounced effect of the magnetic field itself on the adhesion of these bacteria to the surface of the polymeric biomaterial, to which magnetic nanoparticles were not added, was revealed. And this, in turn, was not observed in the case of lactobacilli," says Anton Bonartsev, head of the work, associate professor of the Department of Bioengineering of the Faculty of Biology. "Thus, we have shown the ability to regulate the adhesion of bacteria to polymeric biomaterials both with the help of the piezoelectric effect and with the help of a direct effect of the magnetic field, and both factors acted in completely different ways on Gram-negative and Gram-positive bacteria."

The obtained results are very important for several promising areas in bioengineering: the development of new implantable piezoactive biomaterials with an externally controlled magnetic field effect on cells and tissues, the creation of piezoactive implants resistant to bacterial infection and the formation of biofilms on their surface, the creation of bioreactors with the growth of bacteria and animal cells on biopolymer carriers stimulated by a magnetic field, the creation of magnetically controlled field of biosensors for diagnosing the adhesion ability of various bacteria and other areas. Expanding our knowledge of such new phenomena at the intersection of biology, chemistry, physics and medicine, as the influence of the piezoelectric effect of biomaterials on the behavior of cells, is possible only through such complex interdisciplinary research."

 

[Lalas]

Artificial Intelligence of the Russian Federation

National Portal in the Field of Artificial Intelligence

Национальная стратегия

ai.gov.ru

National strategy
The National Strategy for the Development of AI for the period up to 2030 was approved by the Decree of the President of the Russian Federation dated 10.10.2019 No. 490.

Federal Project "Artificial Intelligence"
Approved in 2021 for the implementation of the National Strategy.

Правовое регулирование ИИ в России, регуляторика И (нейросетей)

Правовое регулирование ИИ в Российской Федерации, информация о регулировании работ и услуг, связанных с искусственным интеллектом и нейросетями

ai.gov.ru

Regulation

In 2020, the Government of the Russian Federation approved the Concept of Regulatory Regulation of AI. This will make it possible to develop technology and respect the rights of citizens, ensure the security of the individual, society and the state.

AI Assignments
Regulation in the field of AI is carried out on the basis of instructions of the President of the Russian Federation.

Current instructions for 2023:

- establish mandatory requirements to improve the efficiency of business entities and their mandatory use of modern technologies, including AI technologies (if such entities are provided with subsidies from the federal budget)

- to make changes to the educational programs of universities that will increase the level of competence in the field of AI of specialists in key sectors of the economy and the social sphere, specialists in state and municipal administration

- Make changes to national projects and state programs that provide for the introduction of artificial intelligence technologies in each industry.

- adjust strategies for the digital transformation of economic sectors

- monitor the results of the use of AI technologies
ensure the participation of the Federal Center of Competence in the Field of Labor Productivity in the implementation of AI technologies and modern management systems in the sectors of the economy, the social sphere and government agencies

- to approve the federal project for the development of domestic robotics: to determine the legal, tax and other conditions related to the development of production in this area, measures of state support, target parameters for the development of production and the introduction of industrial robots

- extend support for AI research centers until 2030

- include measures for the introduction of AI technologies as a priority task in the investment development programs of companies with state participation


The Government of the Russian Federation, together with the Alliance in the Field of Artificial Intelligence, shall ensure:

a) changes in the established norms that impede the introduction of AI in the sectors of the economy and the social sphere;

b) creating more favorable conditions for the export of domestic AI products;

c) expanding the list of territories where unmanned aircraft systems are being tested;

d) establishment of an award for young scientists and engineers for breakthrough solutions in the field of AI, as well as for domestic companies for the successful implementation of the technology;

e) creation of a list of current technological areas in the field of AI;

f) introduction by economic entities of a unified system for evaluating domestic solutions with AI technologies;

g) creation of a ranking of universities in terms of the quality of training of specialists in the field of AI;

h) develop and implement measures for the development and implementation of domestic cloud technologies and platforms;


The Government of the Russian Federation, together with the commissions of the State Council of the Russian Federation, the Federal Center of Competence in the Field of Labor Productivity, and the Alliance in the Field of Artificial Intelligence Association, should ensure the transition of the system of state power at the federal and regional levels to a management model based on automatic collection and analysis of data using information platforms

The Presidential Administration of the Russian Federation, together with the Government and the Alliance in the Field of Artificial Intelligence Association, will prepare a draft presidential decree on amendments to the National Strategy for the Development of Artificial Intelligence for the period up to 2030, aimed, among other things, at the widespread introduction of AI

The Ministry of Health of the Russian Federation, the Ministry of Economic Development of the Russian Federation and the Ministry of Digital Development of the Russian Federation shall ensure:

a) the use of the results of medical research obtained with the help of AI in clinical results for the compulsory medical insurance system;

b) creation of open databases with anonymized medical information

Commissions of the State Council of the Russian Federation to introduce the most successful practices in the use of AI in the constituent entities of the Russian Federation

The Federal Tax Service of Russia, together with the Ministry of Economic Development and the Ministry of Digital Development, take measures aimed at ensuring the effective use of the mechanism of tax incentives for entrepreneurs who have introduced advanced domestic information and telecommunication technologies

recommend the Alliance in the Field of Artificial Intelligence to submit proposals on additional measures to support projects and specialists in the field of AI, on providing domestic software developers with access to databases for the development of AI programs, and advise organizations

Rosatom State Corporation, together with Russian Railways and with the participation of the Ministry of Digital Development of Russia and Sberbank of Russia and leading research universities in the field of artificial intelligence, will hold conferences on the use of new computing and data transmission technologies

The Ministry of Industry and Trade of Russia will hold conferences on the use of new industrial technologies starting in 2023

Recommend that the State Duma consider a draft federal law establishing the procedure for depersonalization of personal data


In addition to the instructions of the President of the Russian Federation, AI in Russia is regulated by decrees of the President of the Russian Federation, resolutions and orders of the Government of the Russian Federation and the Ministry of Transport of the Russian Federation.

Experimental legal regimes
The development of AI is also supported through the introduction of experimental legal regimes (EPRs)

Federal Law of 31.07.2020 No. 258-FZ "On Experimental Legal Regimes in the Field of Digital Innovations in the Russian Federation",
Federal Law No. 331-FZ of 02.07.2021 "On Amendments to Certain Legislative Acts of the Russian Federation in Connection with the Adoption of the Federal Law "On Experimental Legal Regimes in the Field of Digital Innovations in the Russian Federation"

Новости национального портала искусственного интеллекта и нейросетей в РФ

Актуальные новости от национального портала искусственного интеллекта и нейросетей в РФ

ai.gov.ru

news

ВЭФ назвал дипфейки и ИИ главными угрозами для выборов в разных странах | Новости национального портала искусственного интеллекта РФ

ВЭФ назвал дипфейки и ИИ главными угрозами для выборов в разных странах | Актуальные новости национального портала искусственного интеллекта, интересные новости из мира нейросетей

ai.gov.ru

WEF Names Deepfakes and AI as Top Threats to Elections in Different Countries

12.01.2024

Deepfakes combined with phishing attacks could disrupt elections around the world in 2024, WEF experts concluded. There are already examples of such manipulation of voters' minds.

Deepfakes can interfere with democratic processes, according to a report by the World Economic Forum (WEF) and Accenture, published on Thursday, January 11.

What is a deepfake?
This is an image generation technique based on artificial intelligence, the algorithms of which are trained to change elements on existing videos, audio files, and photos.

Together with sophisticated phishing campaigns, deepfakes can become a weapon to disrupt democratic elections, the document says. In 2024, more than 45 countries are set to hold elections, including Russia, the United States, the EU, and India. More than half of the world's population can take part in these elections, which is why the media has already called 2024 the "mother of all election years" and the "Democratic Super Bowl".

As noted in the WEF report, AI-generated deepfake videos or audio recordings can be used to spread false information about candidates or manipulate public opinion. They cite the example of the elections in Slovakia in September 2023, when a deepfake audio clip was released, from which it followed that one of the candidates allegedly discussed with a media representative how to carry out manipulations.

In addition to deepfakes, the WEF mentions automated disinformation, where artificial intelligence algorithms reproduce large amounts of disinformation, making it difficult to combat it, as well as targeted advertising, which can be used by artificial intelligence to manipulate opinions or suppress voter turnout.

In addition, the authors of the report point out possible problems with data privacy: information for voting can be obtained from identification documents, residence records, automatic processing of this data can lead to leaks. Finally, with the help of artificial intelligence algorithms, attackers can manipulate public opinion on social networks, amplifying the effect of some political messages and suppressing others.

In August last year, The Guardian reported that artificial intelligence could affect the outcome of the 2024 US presidential election. Experts interviewed by the publication warned that thanks to this rapidly developing technology, it will be possible to adopt the disinformation tactics of the past and "breathe new life into it."

The report cites an example of one of the most advanced and sophisticated social engineering attacks, in which artificial intelligence was used to attack a software company. In August 2023, an employee of the company received a deepfake audio recording about the recruitment of health insurance participants, clicked on a link in it, providing their credentials to the fake system. Immediately afterward, the attacker called the employee's phone to get a multi-factor authentication code. These actions aroused the employee's suspicions, but since the attacker used a fake audio recording of a colleague's acquaintance, the employee still shared the code. Using the credentials and this code, the attacker was able to add their personal device to the employee's account, which in turn allowed them to authenticate with the company. In Russia, users of messengers faced cases of using generated audio messages, RBC wrote.

Эксперты Давоса назвали дезинформацию главной мировой проблемой | Новости национального портала искусственного интеллекта РФ

Эксперты Давоса назвали дезинформацию главной мировой проблемой | Актуальные новости национального портала искусственного интеллекта, интересные новости из мира нейросетей

ai.gov.ru

Davos experts call disinformation the world's main problem

11.01.2024

In the report of the Davos forum, disinformation took the first place in the list of short-term risks for the first time. The list of long-term threats is dominated by natural threats: climate change, biodiversity loss, and lack of resources.

Misinformation and misinformation have topped the list of the biggest short-term global risks for the first time, while extreme weather and critical climate change are the biggest long-term concerns. This is stated in the Global Risks Report published on January 10, prepared by the World Economic Forum. The study was written on the basis of a survey of 1,490 forum experts and was released five days before the annual forum in Davos, which will be held from January 15 to 19.

Thus, the main risks in the field of "Technology" were attributed to disinformation by 53% of the surveyed experts, followed by cyberattacks and the adverse consequences of artificial intelligence technologies. According to experts, disinformation poses the greatest risk in the short term - within the next two years. Also on the list of short-term risks:

- extreme weather conditions;

- social or political polarization;

- Inter-State armed conflicts;

- Lack of economic opportunities;

- inflation;

- forced migration;

- recession;

- pollution.

"Disinformation has rapidly risen in the rankings to the top spot over a two-year period, and the risk is likely to become more acute as elections are held in several countries this year," the report said.

Experts note that the spread of disinformation no longer requires special skills and can be carried out with the help of artificial intelligence (AI), which has already led to "an explosive growth of falsified information and so-called synthetic content - from sophisticated voice cloning to fake websites."

The mass adoption of AI in 2023 is also due to the growing popularity of the ChatGPT chatbot, which was trained using an array of texts from the Internet and dialogues with real users. Along with it, many other similar services appeared, including the Russian YandexGPT.

At the end of March, businessman Elon Musk, Pinterest co-founder Evan Sharp, Apple co-founder Steve Wozniak and other entrepreneurs and representatives of the IT industry signed an open letter demanding to suspend the development of neural networks more powerful than GPT-4 for at least six months. In total, the letter was signed by more than 1 thousand IT specialists. They warned that AI systems with human-comparable intelligence could pose a danger to society, and questioned whether humans should "risk losing control of civilization."

According to the authors of the report, the list of long-term risks (within ten years) is headed by environmental risks. So, in addition to extreme weather conditions, experts fear critical climate change, loss of biodiversity and ecosystem collapse, as well as a shortage of natural resources. Disinformation is only on the fifth line of this list.

As the authors pointed out, the effects of the COVID-19 pandemic and the effects of the ongoing conflict in Ukraine "have exposed cracks in societies that are further expanding due to episodic shocks." Still, the global system has been "remarkably resilient," and a widely expected recession last year has not materialized, the report said.

The Forum's Risk Perceptions Survey 2023-2024 (GRPS) revealed a largely negative perception of the future of the world in the short term. Thus, the majority of respondents (54%) expect some instability and moderate risk of global catastrophes, while 27% expect more turbulence, and 3% expect global catastrophic risks to materialize in the short term. Only 16% predict a stable or calm period.

Last year, experts identified the main short-term risk as the cost of living appreciation. In second place are natural disasters, including those associated with extreme temperatures. The top five risks, ranked by impact, also included: the growth of geo-economic confrontation, the failure of attempts to mitigate climate change, and the polarization of society.

In the long term, experts then highlighted the risks of failure of attempts to mitigate climate change. In their opinion, the second most important threat in this context will be the risk of failure to adapt to climate change, the third place will be taken by risks associated with natural disasters, the fourth most important is the decline in biodiversity, and large-scale forced migration closed the top five.

Ученые собрали первый процессор из клеток мозга | Новости национального портала искусственного интеллекта РФ

Ученые собрали первый процессор из клеток мозга | Актуальные новости национального портала искусственного интеллекта, интересные новости из мира нейросетей

ai.gov.ru

Scientists have assembled the first processor from brain cells

11.01.2024

In the United States, they created a hybrid processor from electronic components and a brain organoid grown from human stem cells. The system is capable of speech recognition and solving nonlinear equations. Biocomputers have been developed for about twenty years, and this is the first real result.

Based on the Principle of the Brain
The human brain contains about 86 billion neurons and up to a quadrillion synapses. Each cell is connected to thousands of others, constantly responding to incoming signals and interacting with each other. The most modern processors are still able to recreate only a small part of this unique natural system.

In 2018, Chinese scientists simulated just one second of brain activity using the fastest supercomputer at the time, Sunway Taihulight. It took a machine with 10.5 million processor cores four minutes to do that, even though it occupies 1,000 square meters and consumes 16 megawatts of power. For comparison, a human brain with a volume of about two liters requires less energy than a typical light bulb.

Machine learning algorithms and artificial neural network models are becoming increasingly complex. And productivity and energy efficiency are becoming key drivers of the pace of technological progress.

Modern computer technologies are developing in two main directions: logical and neuromorphic. The first is focused on the creation of more and more powerful and productive machines, built according to the traditional principle. The second is to develop computer systems that mimic the functioning of the human brain, and eventually to create an artificial analogue of it.

One of the secrets of the brain's efficiency is that its cells – neurons – act as both processors and memory devices. And in most modern computing devices, these two functional blocks are separated.

Neuromorphic processors are built on the principle of neuronal interaction. The basis is computing cores combined into neural networks, which usually consist of ordinary transistors. Each nucleus, which operates as several hundred neurons, has its own SRAM-type RAM, a task scheduler, and a router to communicate with other nuclei. An integrated circuit of a neuromorphic processor can contain thousands of such cores.

For example, Cerebras' experimental CS-1 superprocessor contains 1.2 trillion transistors organized into 400,000 compute cores with 18 gigabytes of local distributed SRAM memory. The cores are fully programmable and optimized to work with any neural network. The total performance of the system is 100 petabits per second.

Neuromorphic devices are used for computer vision, voice recognition systems, automatic word processing, search engines, and other applications that require machine learning, including neural networks. Without them, it is impossible to imagine the development of unmanned technologies and industrial robotics.

A separate area of AI development is neurohybrid systems that combine artificial and natural neural networks. The neuromorphic chips in them are connected to living nerve cells.

Neurohybrid systems have been actively studied since the early 2000s, when the first experiments were conducted to train a neuronal culture - a network of tens of thousands of living neurons grown "in vitro". Then, models of combining culture with virtual and then real processors began to appear. So far, the main field of application of such systems is neuroprosthetics and the creation of biosensors. But in the future, they may become the basis of a new generation of computer technologies.

Living Cell Processor
All forms of life—from individual cells receiving chemical signals to complex organisms moving through the environment—process information. Scientists are trying to combine "living" processors with electronic circuits to create biocomputers - high-performance intelligent machines that run on a small amount of energy.

Last year, American scientists led by Thomas Hartung of Johns Hopkins University presented a new vision for the development of neurohybrid systems, which they called the concept of "organoid intelligence." In contrast to the AI approach, in which they try to make the computer more similar to the human brain, here it is proposed to use the brain cells themselves as computational elements, placing them on the processor board.

Recently, another group of American specialists, led by engineer Feng Guo of Indiana University in Bloomington, reported that they had created a bioprocessor based on this principle and successfully tested it on tasks such as speech recognition and predicting solutions to nonlinear equations.

The system, called Brainoware, is a chip-connected "mini-brain" — an organoid made from neurons grown from human pluripotent stem cells. The researchers placed a fragment of cultured nerve tissue on a plate with thousands of electrodes connecting input and output devices, which used conventional computers.

Scientists have proven that Brainoware can work like a neural processor - receiving, remembering and processing information. The organoid's neural network is capable of converting sounds into a set of electrical signals. If you put a sensor at the output that decodes them using machine learning algorithms, you get a ready-made speech recognition system.

Biocomputer Capabilities
To demonstrate the potential of the Brainoware system, the researchers presented it with 240 audio recordings made by eight Japanese-speaking men. After two days of training, Brainoware was able to identify a specific person's voice with 78 percent accuracy. Scientists note that for the first experiment of a fundamentally new computer technology, this is a very good result. Existing speech recognition systems that use artificial neural network algorithms have higher accuracy. But they need an order of magnitude more time to learn.

Another area in which the authors have tested their invention is reservoir computing, which is used to predict dynamical systems. This is one of the most difficult areas of applied mathematics, which only neural networks can cope with.

In particular, the researchers asked Brainoware to compute the Mainaut mapping, one of the most studied dynamical systems exhibiting chaotic behavior, which is described using nonlinear equations. After four days of self-study without human intervention, the biocomputer was able to predict the behavior of the system with greater accuracy than an artificial neural network working only with a short-term memory unit.

"Due to the high plasticity and adaptability of the organoid, Brainoware can change and reorganize in response to electrical stimulation, proving its capacity for reservoir computing," the authors write.

The researchers emphasize that the human brain functions in a similar way. It is not pre-tuned to solve any particular task. But thanks to its plasticity and adaptability, the main features that distinguish it from a machine, it is absolutely versatile and can be used in any situation.

So far, scientists have managed to create a prototype of only one of the elements of the future biocomputer, albeit a key one. It will take years, perhaps decades, to develop a full-fledged system, the authors note. At the same time, in addition to solving purely technological problems, it is necessary to find answers to ethical questions. The use of living human nervous tissue in industrial products is likely to require the adoption of special regulations.

 

[Lalas]

Ученые предложили новый взгляд на загадку памяти - Российская газета

Настоящей сенсацией стало сообщение научного руководителя Института высшей нервной деятельности РАН академика Павла Балабана на заседании президиума академии. Он рассказал об экспериментах, которые заставляют переосмыслить парадигму о работе мозга, в частности о механизме формирования...

rg.ru

16.01.2024
Scientists have proposed a new look at the mystery of memory

A real sensation was the report of the scientific director of the Institute of Higher Nervous Activity of the Russian Academy of Sciences, Academician Pavel Balaban, at a meeting of the Presidium of the Academy. He spoke about experiments that make us rethink the paradigm about how the brain works, in particular, about the mechanism of long-term memory formation. A correspondent of "RG" talks about this with the scientist.

Pavel Miloslavovich, science has been trying to unravel what memory is for many years. Tens of thousands of experiments have been conducted, various hypotheses have been proposed, but the answer has not been found. Scientists have to admit that we don't know what the brain is, what memory is. You're talking about rethinking the current understanding of the brain. What do you mean?

Pavel Balaban: These ideas are almost based on the postulate: the main actor in the brain is neurons. Now, it turns out that this is a big misconception.

Did you bet on the wrong person? Who is the favorite who comes out of the shadows?

Pavel Balaban: These are the so-called glial cells, or astrocytes. Interestingly, there are almost 10 times more of them in the brain than neurons, they are the main population of the brain, but their functions were almost unknown. It was believed that astrocytes were something secondary, a kind of utility room for feeding neurons. However, recent experiments have shown that the opposite is true! That the key participant in the formation of memory is not neurons at all, but astrocytes.

How did you manage to see this?

Pavel Balaban: For example, British scientists in experiments on mollusks stumbled upon a strange effect. Their short-term memory of the event did not immediately turn into long-term memory. Tests have shown that there is no memory for about an hour after training. And it took 3-4 hours to form a full-fledged memory. This mysterious period has baffled scientists: Where has she been hiding all this time?

Tests have shown that there is no memory for about an hour after training. This mysterious period has baffled scientists: Where was she hiding at this time?

Almost at the same time, we conducted similar experiments on snails and saw the same phenomenon. After training, the memory disappeared somewhere, and then suddenly resurfaced.

And how did you manage to fix these memory tricks in the first place? Tell us more about these subtle experiments.

Pavel Balaban: In the beginning, we give food to the snails, combining it with a neutral smell. And then there is only the smell, and we see that the animal immediately begins to look for food. That is, he has formed a short-term memory for the tandem smell and food. Everything seems to be as it should be. But we continued the experiment. They started smelling every ten minutes, and that's when the surprises began. The snails stopped reacting to him altogether. And this silence lasted for about an hour, and then the animals suddenly "woke up." It was as if the memory of the smell had returned to them, and they began to look for food again.

That is, short-term memory turned into long-term memory only after a few hours? And where had she been hiding for so long?

Pavel Balaban: As it becomes clear now, in those glial cells, astrocytes, to which no one paid attention. It becomes clear that nature has created a rather sophisticated mechanism for the formation of long-term memory. In general terms, it works something like this. First, neurons respond to external stimuli that need to be remembered. It can be anything - a smell, a portrait of a person, a match score, etc. At the same time, neurons release specific hormones into the environment. Then diffusion is switched on - hormones penetrate to their neighbors, to glial cells. And in response, they produce their own substances and send them back to neurons. It is this mutual diffusion that takes hours. In this long interval, the importance of whether or not it is necessary to remember a smell, a portrait or an account for a long time is assessed.

Evaluated by whom? I looked at the portrait of Pushkin. How do I remember it?

Pavel Balaban: The fact of the matter is that there are possible options here. Pushkin can either remain in your memory or pass by. It all depends on how strong the trace of the image of Pushkin has remained in your neurons since the moment you first saw it.

But if there is a trace, does it mean that Pushkin has already been imprinted forever?

Pavel Balaban: No. Only a trace is not enough, as the experiment with snails showed. The information is stored in long-term memory only after a response from glial cells. Figuratively speaking, this interval of hours is given to the brain to assess whether you need to memorize Pushkin or not. How important this information is to you.

So the trail and the response from the astrocytes are like two keys to open a safe?

Pavel Balaban: That's right. The signal from the astrocytes does not encode the memory, but without it you will not open the safe.

And why such a complex system at all? Wait for a response from the astrocyte? Couldn't it be simpler: the neuron reacted, remembered, and the image is imprinted for a long time.

Pavel Balaban: But then the brain will remember everything. And the vault will quickly overflow! And when working on the principle of "keys to the safe", there is a selection. The garbage is separated! The brain has plenty of time to select the important and weed out the secondary.

So, in the safes of long-term memory there is a variety of information that is important for each of us. But why do we often forget it? A person has studied geography, but does not remember, for example, that Brussels is the capital of Belgium!

Pavel Balaban: Maybe this information was not important to him, and the necessary hormones in neurons were not developed to form a trace. But sensory images remain in the memory. If you show a person hundreds of capitals, then when he sees Brussels, he will remember that he has already seen this somewhere, but he cannot connect it with Belgium. There is no connection between the two in his brain. But we already know how it can be restored. The word "Brussels" will bring to mind Belgium.

Get your memory back? Make a straight-A student? Is this even possible?

Pavel Balaban: Possibly. I will try to explain in the most general terms. We'll have to turn to genetics. As I said, when memory is formed, astrocytes send back signals to the neuron. So, they regulate the activity of the genes of those neurons that are associated with long-term memory. This is the essence of the mechanism of its formation. That is, memory is directly related to the work of genes.

But then it's really a breakthrough! Today, changes in gene activity are a global trend. Does this mean that it is possible to restore memory with the help of this technology?

Pavel Balaban: Absolutely. This was demonstrated by giving our snails an injection of a special drug. Their memory was completely restored.

How can we use this knowledge to help a person?

Pavel Balaban: First of all, it should be emphasized that we are witnessing a paradigm shift. It is safe to say that the main "population" of the brain is no longer neurons, but astrocytes. They play a crucial role in the formation of long-term memory. And this radically changes the entire approach to the fight against cognitive diseases, including Alzheimer's, dementia and many others. If earlier the main target of research was neurons, now it should be glial cells, astrocytes. We know where to look, where to go. And this is the most important thing in science.

The paradigm shift is a revolution in science. How did your colleagues react to this work? History shows that at first, revolutionary ideas, and even more so paradigm shifts, are hit by an avalanche of criticism. It takes a long time for the scientific community to accept the new view. Have you received your portion yet?

Pavel Balaban: This is the most recent work, we are just preparing the article for publication. So the whole discussion is yet to come.

https://kz.kursiv.media/2024-01-18/zhrb-robot-sud/

A robot bailiff has been launched in Kazakhstan.
The authorities believe that it will help save up to two billion tenge
January 18, 2024

A robot bailiff has appeared in Kazakhstan. It will send SMS messages to citizens about fines for administrative offenses after 50 days of non-payment. The authorities believe that this will help Kazakhstanis save up to two billion tenge.

An unusual project in Taraz was launched by the Ministry of Justice and the Republican Chamber of Private Bailiffs. The press service of the department noted that the robot is being introduced for simplified enforcement proceedings.

"Previously, citizens had to pay up to 25% of the amount of the fine to the CSI in case of late repayment of the imposed fine, but now this function is performed by a robot for free," the message says.

According to preliminary calculations, the robot will help Kazakhstanis save up to two billion tenge. If the project is successful, the authorities plan to scale it up to the whole of Kazakhstan.

How does a robot ship executor work?

The Committee on Legal Statistics and Special Accounts of the Prosecutor General's Office sends an order to recover the amount of the fine for an administrative offense after 50 days of non-payment.

The robot sends an SMS notification about the need to fulfill the requirement within 5 calendar days.

In the absence of payment for voluntary repayment, the system transfers the enforcement document for enforcement of the CSI.

If the payment is made on time, the enforcement proceedings are terminated without extra costs

Ученые смогли восстановить память человека с помощью чипов - Российская газета

Уникальный эксперимент провели американские ученые из Стэнфордского университета. Они встроили в мозг чипы-имплантаты. Они стимулировали зоны, которые отвечают за умственные способности, в частности, кратковременную и долговременную память. Конкретно речь идет о стимуляции латеральных...

rg.ru

Scientists were able to restore human memory with the help of chips
26.12.2023

A unique experiment was conducted by American scientists from Stanford University. They built implant chips into the brain. They stimulated areas that are responsible for mental abilities, in particular, short-term and long-term memory. Specifically, we are talking about the stimulation of the lateral central nuclei of the thalamus in each hemisphere.

The study involved five people aged 22-60 years. All of them had suffered severe brain injuries, as a result of which they experienced problems with their mental abilities. During the experiment, which lasted three months, the chips sent signals to the brain for 12 hours a day. At the end of the experiments, all participants underwent tests of mental abilities, namely working memory and concentration. As the authors of the study report in Nature Medicine, the volunteers' attention and ability to remember improved by more than 30 percent. In addition, they were 32 percent faster.

The scientists continued the experiment by disabling one of the patients' brain chips for three weeks. Repeated tests showed that his mental abilities had dropped by 34 percent again, the same as before the surgery. Thus, in order to improve brain function, the implant must work every day. But the most important thing is that an electronic device can actually improve brain function.

 

[Lalas]

Российский фиджитал-спорт пришел в Африку - Российская газета

В столице Татарстана 15 января 2024 года прошел уникальный международный турнир по фиджитал-спорту в двух дисциплинах: фиджитал-футбол и фиджитал-гонки. В нем вместе с российскими спортсменами приняли участие 20 студентов казанских университетов из Замбии, Нигерии, Камеруна, ЮАР, Бенина...

rg.ru

Russian phygital sport has come to Africa

On January 15, 2024, the capital of Tatarstan hosted a unique international phygital sports tournament in two disciplines: phygital football and phygital racing. Together with Russian athletes, 20 students of Kazan universities from Zambia, Nigeria, Cameroon, South Africa, Benin, Namibia, Zimbabwe, Malawi, Botswana and other African countries took part in it.

Phygital is a completely new sport that combines competitions in virtual space and classic sports. Its name is derived from a combination of the English words physical and digital, which means "functional and digital sport" in Russian. In Russia, it was officially recognized as a sport a year ago - in January 2023. Phygital combines the best of virtual and physical sports, tests both the physical fitness of athletes and their digital skills, and debunks stereotypes about sedentary gamers - it is impossible to achieve high results in phygital competitions without good physical fitness.

As part of the tournament, students from Africa got acquainted with phygital disciplines and were able to show their abilities in a new exciting field. The tournament became a stimulus for the development of phygital sports in Africa, opening up new prospects and opportunities for the inhabitants of the continent for self-expression in sports. Its participants had the opportunity to plunge into the hospitable atmosphere and establish friendly contacts. The tournament has become not only a sporting event, but also an example of cultural exchange on an international scale.

"Tatarstan headed by the Rais of the Republic Rustam Nurgalievich Minnikhanov always tries to promote the merits of our country," said the Minister of Digital Development of the Republic of Tatarstan Airat Khairullin, who was present at the tournament.
"The Games of the Future have not been left out either. Phygital sport, invented in Russia by Deputy Prime Minister Dmitry Chernyshenko, is a huge step towards creating friendly relations with the whole world."

"Phygital games harmoniously develop a person," said Aziz Zamaliev, Vice President of the Federation of Phygital Sports of the Republic of Tatarstan. - We can be proud of it and spread it all over the world. Africa is a fast-growing continent that wants to be in trend with global trends. This year we will hold at least five championships in different countries of the African continent."

According to the results of the competition, the winners of the tournament were awarded certificates and valuable prizes, the rest of the participants received letters of gratitude.

Ученые из России и США создали вещество, которое может победить ВИЧ - Российская газета

Разработанная учеными молекула, без всякого преувеличения, может стать одним из самых громких прорывов последнего времени в мировой науке. Если говорить совсем просто, то в российской лаборатории создан "киллер" ВИЧ.

rg.ru

Scientists from Russia and the United States have created a substance that can defeat HIV

18.12.2023

The molecule developed by scientists, without any exaggeration, can become one of the most high-profile breakthroughs of recent times in world science. To put it simply, a "killer" of HIV has been created in a Russian laboratory.
...
Today, several tens of millions of infected people have been recorded on the planet, for example, in Russia there are about 800 thousand of them. And that's just the official statistics.
...
"Alas, no modern drugs can kill it, it stays with a person forever," says Vadim Makarov, head of the laboratory of the Federal Research Center of Biotechnology of the Russian Academy of Sciences. -Why? The fact is that the immunodeficiency virus turned out to be very sophisticated. First of all, it is very small, so it is difficult to find targets to kill it. But most importantly, it has found a very safe haven for itself - our neurons.
...
Scientists from the Federal Research Center of Biotechnology of the Russian Academy of Sciences and the University of North Carolina (USA) have set the task of killing the virus in its lair - the neurons themselves. The "killer" must meet at least three requirements: penetrate the barrier into the neurons, kill the enemy there, and not harm the neurons themselves. It took scientists more than five years to combine these three criteria in a single molecule. Some may ask: why is it taking so long? The fact is that the requirements are contradictory. By aiming to accomplish one thing, you may go beyond a critical threshold for others. For example, there are drugs that can penetrate the barrier, but they are very toxins to the neuron. And this leads to various neurodegenerative diseases. In fact, in this case, the scientists solved the difficult problem of optimizing the requirements.

- This work was carried out in stages. We came up with a substance, then synthesized it and sent it to the United States, where it was tested on different strains," says Vadim Makarov. - Having received the results from them, we made certain changes to our molecule and synthesized a new compound, which was again tested by the Americans.

In search of the "killer", dozens of different options were passed through the conveyor and sifted out, until finally the desired result was obtained. Optimum for all three criteria. The created compound penetrates through the barrier into neurons, does not harm them and kills the virus. This was confirmed by animal tests. Why was the testing done in the USA? After all, in many laboratories anyone can be tested for HIV?

"Yes, we have tests to detect the virus in the human body, but we have not yet created tests for various chemical compounds that test their activity, safety, and ability to penetrate neurons, so we worked with the Americans," Makarov explains.

So, the stage of fundamental research is over, and the transformation of the knowledge gained into a real medicine that will save humanity from a terrible disease is ahead.

Искусственный интеллект и роботизация повлияют на рынок труда в России - Российская газета

Искусственный интеллект и роботизация окажут влияние на российский рынок труда больше, чем другие технологии, считают участники опроса, проведенного "Яков и Партнёры" и hh.ru.

rg.ru

12.12.2023

Artificial Intelligence and Robotics Will Affect the Labor Market in Russia

Artificial intelligence and robotics will have a greater impact on the Russian labor market than other technologies, according to participants in a survey conducted by Yakov & Partners and hh.ru.

In their opinion, the top five technologies in terms of influencing the labor market are the automation of business processes using advanced analytics, robotics, generative artificial intelligence, big data and additive manufacturing. Green energy and metaverses took the last lines in this ranking, with less than half of respondents believing in their impact on productivity and jobs.

IT workers are the most confident in the impact of the Internet of Things, but the least confident in the importance of blockchain technologies for the labor market. Employees in the service sector are more likely to believe in the importance of generative artificial intelligence: among them, this technology took first place compared to third for all other respondents, the authors of the study clarify.

"Typically, employees of large companies are one and a half times more likely to say that their organizations are already using new technologies. This is especially evident in the field of big data, robotics, and advanced analytics. But it is these technologies that have the most significant potential to increase labor productivity, which means that they may be the best means of mitigating the shortage of personnel in the market. Probably, it is necessary to raise awareness of the opportunities and improve the availability of these technologies, including for medium and small businesses," said Elena Kuznetsova, co-author of the report, director of the Yakov & Partners Research Institute.

The survey involved 700 respondents from companies of different industries and sizes.

В Белгороде создали робота-шахтера - Российская газета

Специалисты Белгородского госуниверситета разработали автоматическое самоходное устройство для работы в железорудных шахтах.

rg.ru

A robot miner was created in Belgorod

12.01.2024
Specialists of Belgorod State University have developed an automatic self-propelled device for work in iron ore mines.

"The Atlas rail drone is designed to perform measurement work underground and has no analogues in Russia," Ignat Ignatenko, head of the project, head of the Department of Applied Geology and Mining, told TASS.

At present, the necessary underground measurements are carried out manually by surveyors - often in dangerous conditions - and are time-consuming. Atlas allows you to speed up the process and make it much safer without losing quality.

Atlas can quickly find places of deformation of mine workings and rail tracks. This prevents derailment of rolling stock, reducing losses from equipment downtime. And most importantly, it minimizes emergencies in the mine," the scientist continued.

The robot placed on the rails is controlled remotely - by an application from a smartphone. While driving, it measures the width and slope of the track, scanners determine the geometry of the working. "Atlas can work without satellite navigation," Ignatenko said.

The robot miner was created by the university together with the industrial partner of BelSU, the company "Industrial Electronic Systems". It has developed the sensors and other electronics necessary for the drone.

In 2025, it is planned to certify Atlas as a measuring complex and launch the robot into mass production.

Путин поручил увеличить вычислительные мощности суперкомпьютеров в России - Российская газета

Президент РФ Владимир Путин поручил правительству разработать и реализовать комплекс мер, направленный на увеличение вычислительных мощностей суперкомпьютеров в России.

rg.ru

19.01.2024

Putin instructed to increase the computing power of supercomputers in Russia

Russian President Vladimir Putin instructed the government to develop and implement a set of measures aimed at increasing the computing power of supercomputers in Russia.

Such an instruction is contained in the list approved by the head of state following the results of the conference "Journey to the World of Artificial Intelligence", held in November last year.

"Develop and implement a set of measures aimed at increasing the computing power of supercomputers located in the Russian Federation," the document published on the Kremlin's website says. Vladimir Putin also instructed to determine the specific parameters for increasing these capacities.

Another instruction of the president: the government and the Ministry of Foreign Affairs of Russia must think over measures for interaction between Russian developers in the field of artificial intelligence and colleagues from friendly countries by March 31.

Earlier, Vladimir Putin answered the question of whether we should be afraid of artificial intelligence. According to him, it is impossible to prevent the development of AI, including superintelligence. Therefore, it is necessary to do everything so that we can be one of the leaders in this direction, the Russian leader stressed.

Перечень поручений по итогам конференции «Путешествие в мир искусственного интеллекта» • Президент России

Новости, стенограммы, фото и видеозаписи, документы, подписанные Президентом России, информация о деятельности Администрации

www.kremlin.ru

The President approved a list of instructions following the conference "Journey to the World of Artificial Intelligence" held on November 24, 2023.

January 17, 2024

1. The Government of the Russian Federation shall:

a) in order to create breakthrough solutions in the field of artificial intelligence, to submit proposals for additional funding from the federal budget for research and development in the field of generative artificial intelligence, including large generative models, subject to an increase in co-financing from leading Russian organizations and ensuring that they test the technologies obtained as a result of such research and development;

b) as part of the forecast of the need of economic sectors for specialists in the level of education for a five-year period, with the involvement of employers' associations, to conduct an analysis of employers' needs for employees with new skills and competencies, and based on the results of this analysis, to ensure the introduction of changes to professional standards and federal state educational standards.

Deadline: April 30, 2024;

c) when forming the federal project "Artificial Intelligence" as part of the development of the national project "Data Economy", to provide for measures to support the development and implementation of large generative models and technological solutions in the field of artificial intelligence, as well as the creation of infrastructure for their widespread use.

Report – by July 1, 2024;

d) ensure the development of a mechanism for the use of archives of state and municipal bodies, library funds for the creation of data sets, providing for the prompt free submission of the information contained in them to specialists in the field of machine learning, taking into account the restriction of access to information established by the legislation of the Russian Federation;

e) develop and implement a set of measures aimed at increasing the computing power of supercomputers located in the Russian Federation, defining specific parameters for increasing these capacities.

Deadline – March 1, 2024;

(e) Ensure the development of large generative models for use in key sectors of the economy, providing a mechanism for the practical implementation of these models by organizations operating in such industries in order to increase labour productivity.

The report is due by July 1, 2024, and then once every six months.

Responsible: M.V. Mishustin

2. The Government of the Russian Federation, together with the State Duma of the Federal Assembly of the Russian Federation, taking into account the previously given instruction, shall ensure the introduction of amendments to the legislation of the Russian Federation aimed at simplifying the access of economic entities to participate in experimental legal regimes in the field of digital innovations and establishing liability for causing harm to the life, health and property of citizens as a result of testing and using technologies Artificial intelligence.

Report – by February 1, 2024

Responsible: M.V. Mishustin, V.V. Volodin

3. The Government of the Russian Federation, together with the Ministry of Foreign Affairs of the Russian Federation:

a) develop and submit proposals on cooperation between Russian software developers in the field of artificial intelligence and developers of such software from friendly countries, as well as on the procedure for access of developers from these countries to Russian large generative models.

Deadline – March 31, 2024;

b) ensure that issues related to the formation of ethical standards in the field of artificial intelligence, balanced regulation and scientific and technical cooperation in this area are included in the agenda of the meetings of the BRICS association within the framework of the Russian Federation's chairmanship in the association in 2024.

Deadline: March 1, 2024

Responsible: M.V. Mishustin, S.V. Lavrov

4. The Government of the Russian Federation, together with educational institutions of higher education that in 2023 took leading positions in the ranking of such organizations in terms of the quality of training of specialists in the field of artificial intelligence, and the autonomous non-profit educational institution of higher education "Skolkovo Institute of Science and Technology", shall ensure an increase in the target figures for admission to training for these organizations at the expense of budgetary funds in the specialties and areas of training related to the development of artificial intelligence technologies, providing for the expansion of the list of master's degree programs implemented by these organizations and programs for the training of scientific and scientific-pedagogical personnel in postgraduate studies in this area.

Deadline: September 1, 2024

Responsible: M.V. Mishustin, N.Y. Anisimov, D.V. Livanov, V.N. Vasiliev, V.A. Sadovnichy, N.M. Kropachev, A.P. Kuleshov

5. The Government of the Russian Federation, together with the Alliance in the Field of Artificial Intelligence Association, shall ensure the development and approval of an additional professional program in the field of artificial intelligence for the heads of major organizations, professional educational organizations, educational institutions of higher education, federal bodies of state power and bodies of state power of the constituent entities of the Russian Federation, paying special attention to the development of skills and competencies in the use of large generative models and providing for the start of training under such a program no later than April 1, 2024.

Report – by April 15, 2024

Responsible: M.V. Mishustin, N.V. Maltseva

6. The Government of the Russian Federation, together with the Russian Academy of Sciences and the Alliance in the Field of Artificial Intelligence Association, shall develop a mechanism to ensure preferential access for Russian researchers, pupils, students and postgraduates to the computing infrastructure of supercomputers to perform tasks in the field of developing artificial intelligence technologies.

Deadline: March 1, 2024

Responsible: M.V. Mishustin, G.Y. Krasnikov, N.V. Maltseva

7. The Ministry of Education and Science of the Russian Federation, together with the Ministry of Digital Development of the Russian Federation, educational institutions of higher education that took leading positions in the ranking of such organizations in 2023 in terms of the quality of training specialists in the field of artificial intelligence, and the autonomous non-profit educational institution of higher education "Skolkovo Institute of Science and Technology" to implement a set of measures aimed at training world-class development scientists in this field.

Report – by September 1, 2024

Responsible: Falkov V.N., Shadayev M.I., Anisimov N.Yu., Livanov D.V., Vasiliev V.N., Sadovnichy V.A., Kropachev N.M., Kuleshov A.P.

8. The Ministry of Economic Development of the Russian Federation, together with the Alliance in the Field of Artificial Intelligence Association and other interested organizations, shall coordinate the preparation of a declaration on the responsible development and use of large generative models within the framework of the Code of Ethics in the Field of Artificial Intelligence.

Deadline: March 31, 2024

Responsible: Reshetnikov M.G., Maltseva N.V.

9. To recommend that Sberbank of Russia, together with the Alliance in the Field of Artificial Intelligence Association, ensure that the international agenda in the field of artificial intelligence, as well as the ethical aspects of the use of artificial intelligence technologies, are discussed (including with the participation of the BRICS member states) during the conference "Journey to the World of Artificial Intelligence".

Deadline: October 1, 2024

Responsible: Gref G.O., Maltseva N.V.

 

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Встреча с главами муниципальных образований

Владимир Путин провёл встречу с главами муниципальных образований субъектов Российской Федерации – участниками Всероссийского муниципального форума «Малая родина – сила России».

www.kremlin.ru

Vladimir Putin met with the heads of municipalities of the constituent entities of the Russian Federation, participants in the Small Motherland – Russia's Strength All-Russian Municipal Forum.

January 16, 2024

President of Russia Vladimir Putin: Good afternoon, colleagues, friends.

I welcome you all, I am glad to see you.

We will talk together – we have already started talking on the way – about the issues that you deal with on a daily basis, to which you have devoted your life.
...
Digital solutions, digital technologies. Of course, they are being implemented throughout the country, in all sectors. At the municipal level, it is also important to use these technologies. I hope you do. If you have any ideas on this matter, I will be happy to take note of them.

В России создали нейросеть, способную проводить собеседования

Петербургская компания Xenia AI представила нейросеть, способную проводить собеседования на уровне опытного специалиста, — сообщает Ferra.ru. Речь о голосовом ассистенте Ксении, которая может самостоятельно генерировать вопросы и проводить «глубокие» интервью с кандидатами.

russian7.ru

A neural network capable of conducting interviews has been created in Russia

The St. Petersburg-based company Xenia AI has presented a neural network capable of conducting interviews at the level of an experienced specialist, Ferra.ru reports.

We are talking about the voice assistant Ksenia, who can independently generate questions and conduct "in-depth" interviews with candidates. Ksenia can replace the recruiter at the stage of the initial screening (selection) of candidates, which significantly reduces the cost and time of finding suitable personnel. A recruiter can create a vacancy in the system by adding questions through AI or subject matter experts. The interview is conducted at a convenient time without the direct participation of the recruiter, and the system automatically evaluates and ranks candidates.

Multilingual Ksenia

Ksenia is able to "communicate" in Russian and English and is suitable for various positions from simple assistants to highly qualified professionals. AI tests have shown that Ksenia is able to interview up to 80% of all candidates, which is significantly higher than the traditional indicators of a human recruiter of 20-30%.

The founder and CEO of Xenia AI, Nikita Wans, highlights the significant benefits of AI technology in hiring. Their use not only speeds up and simplifies the selection process, but also increases the prestige of the company and the brand, especially on the part of candidates for technical specialties, who themselves are well versed in the intricacies of neural network technologies.

How Ksenia works
Ksenia uses machine learning algorithms to generate questions based on the job description and the candidate's profile. The questions can be either open-ended or closed-ended, and they cover various aspects of the candidate's qualifications and experience.

Ksenia also uses artificial intelligence to evaluate candidates' answers. The system takes into account not only the content of the answers, but also their structure, sequence, as well as the candidate's non-verbal cues, such as tone of voice and facial expressions.

In the future, AI interview technology may become even more prevalent. As technology advances, neural assistants will be able to conduct more complex and meaningful interviews, allowing companies to recruit even more effectively.

Медведев заявил, что Россия не сдает своих позиций в науке, несмотря на санкции

Об этом свидетельствует в том числе количество работ, представленных на соискание премии президента РФ в области науки и инноваций, отметил зампред Совбеза РФ

nauka.tass.ru

Medvedev said that Russia does not give up its position in science, despite the sanctions

This is evidenced, among other things, by the number of works submitted for the Prize of the President of the Russian Federation in the field of science and innovation, said the Deputy Chairman of the Security Council of the Russian Federation

MOSCOW, January 18, 2023. Russia does not give up its position in the scientific sphere, despite the sanctions, this is evidenced, among other things, by the number of works submitted for the Presidential Prize in the field of science and innovation. This was stated by Deputy Chairman of the Security Council of the Russian Federation Dmitry Medvedev.

At a meeting of the Presidium of the Presidential Council for Science and Education for young scientists, he stressed that the presence of such high-level scientific works is very important in the context of sanctions, scientific blockades and restrictions, since it testifies to the high potential of Russian science.

"And whether someone likes it or not, we really do not give up our positions, the work is competitive at the world level. The more such work there is, the better," Medvedev said.

He said that the Presidium of the Council for Science and Education is held with the aim of presenting young scientists for the 2023 prize. Research, according to Medvedev, is carried out in various fields and different regions of the country, "which is extremely important." "The most important thing is that they have one thing in common - they are trained by young people who have devoted themselves to science from a young age. They do not yet have an established age, that is, 35 years, but each of them has already established himself as a talented and energetic researcher," the deputy chairman of the Security Council said.

Medvedev recalled that the state provides constant support to young scientists and teams, helps them find their own path and move forward along it.

Самый крупный в России центр генетики и наук о жизни в "Сириусе" планируют расширить вдвое

После расширения площадь центра составит 15 тыс. кв. м

nauka.tass.ru

Russia's largest center for genetics and life sciences in Sirius is planned to be doubled
After the expansion, the area of the center will be 15 thousand square meters

MOSCOW, January 18, 2023. The Sirius Educational Center, where Russia's largest center for genetics and life sciences is located, plans to expand it twice, to 15,000 square meters, Elena Shmeleva, Chairman of the Council of the Sirius Federal Territory, Head of the Educational Center, told reporters at the Russia International Exhibition and Forum.

"7,500 square meters is the largest life sciences center in Russia today, and it will expand to 15,000 square meters," Shmeleva said.

She added that the Educational Center plans to expand other educational and scientific platforms through interaction with strategic partners. According to her, over the eight years of the Educational Center's operation, about 70 thousand schoolchildren have graduated, about 5 million people have been trained on the Sirius Courses platform.

The Scientific Center for Genetics and Life Sciences makes it possible to conduct world-class research in the field of genomics, immunobiology, biomaterials, create gene therapy drugs, and conduct research in the field of plant genome editing.

The Day of the Federal Territory of Sirius takes place on January 18 at the exhibition and forum "Russia" at VDNKh in Moscow. For the first time, a meeting of graduates - pupils of the educational center will be held here.
The International Exhibition and Forum "Russia" takes place from November 4, 2023 to April 12, 2024 at VDNH in Moscow. It is organized to demonstrate the most important achievements of the country in various sectors of the economy, all 89 Russian regions present their expositions. TASS is the general news agency of the forum.

Елена Шмелева рассказала о достижениях федеральной территории «Сириус» на выставке «Россия»

sirius.gov.ru

Elena Shmeleva spoke about the achievements of the Sirius Federal Territory at the Russia exhibition

...
One of the key events of the Federal Territory Day will be a meeting with graduates of Sirius' educational programmes from different years. This year, a unified system of support will be created for Sirius graduates – the most talented young people in the country. The system will help to collect projects, programs and tools that are in demand by graduates at different stages in order to build individual trajectories of their development and self-realization – in the interests of each of them and the entire country.
...
Roman Ivanov, Director of the Scientific Center for Translational Medicine, will talk about how new drugs appear.
...
Residents of the Sirius Innovation Science and Technology Center will point out the latest technological trends and innovations in the field of health, safety and financial technologies.

Pavilion D will be equipped with a zone of master classes, designed primarily for schoolchildren and their parents, on entertaining chemistry, climate change and smart tourism.
...
In the three years since the creation of the federal territory, Sirius has been developing on the verge of its real capabilities and is involved in more and more ambitious projects. This year, Vladimir Putin instructed the Russian Government to endow Sirius with the status of a national methodological center for identifying, supporting and developing talents among children and young people throughout the country. In 2024, regional centres operating on the Sirius model will appear in all regions of Russia. Interregional centers working with children and teachers will also be opened in St. Petersburg and the Kemerovo region.
...
On the federal territory, the construction of a world-class concert complex is nearing completion - the only hall in Europe that can transform the stage for different formats of performances in just 30 minutes. It is expected that in the spring of this year, pupils of the Sirius Educational Center will take to the stage of the concert complex as part of the Constellation competition for young musicians.

In 2024, the federal territory will host major world and federal events. Sirius will host the World Youth Festival, the first BRICS climate summit, and the National Youth Festival of Student Sports Leagues. It will include All-Russian competitions in hockey, artistic gymnastics, boxing, fencing, karate, sailing, taekwondo and other sports.

Work begins on the reconstruction of the former Olympic Village, located in the seaside cluster. It will be turned into a residential quarter for students of the science and technology campus. The project to create a campus will attract even more talented young people to science. Sirius already has all the conditions for this: Sirius University is successfully operating, the second stage of the country's largest laboratory complex in the field of life sciences is being prepared for commissioning, scientific testing grounds for research and advanced developments are being created, and the Innovation Center is being developed to support scientific projects.

As Elena Shmeleva noted, in 2023 Sirius acquired another important scientific area. On Vladimir Putin's instructions, the International Centre for Ecology and Climate Change began its work at the Sirius Presidential Lyceum. In addition to important and relevant research, he will be engaged in the scientific management and examination of educational programs of the Ecology and Biology Center. At least 5,000 people – children and adults – will study at the center. The programmes will focus on education, awareness-raising, research and practical environmental activities. One of these projects will be the "Greening Schools" program, where schoolchildren, their parents and teachers will take part in the improvement of the federal territory. In addition, they will be involved in scientific programs of integrated geo-environmental monitoring at Sirius. The center will have laboratories, a greenhouse, a botanical exposition with information about the flora of the federal territory, a herbarium fund with plant collections, a museum of paleontological finds, mineral and rock samples.

Символика

sirius.gov.ru

At a meeting of the Council on September 12, 2023, the coat of arms of the Sirius federal territory was approved.

 

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Российский 12-кубитный квантовый компьютер впервые применили для обучения нейросетей

На нем тестируются алгоритмы для искусственного интеллекта, который может определять сорт вина по его химическому составу и диагностировать рак молочной железы, сообщили в МФТИ

nauka.tass.ru

A Russian 12-qubit quantum computer was used for the first time to train neural networks

It is testing algorithms for artificial intelligence, which can determine the variety of wine by its chemical composition and diagnose breast cancer, MIPT reported

MOSCOW, January 18, 2023. For the first time, physicists in Russia used a domestic 12-qubit quantum computer based on superconductors to perform calculations related to neural networks and machine learning. The first experiments with this computer confirmed the high speed of its operation, the MIPT press service reported.

"Scientists have launched Russia's first 12-qubit quantum processor for quantum machine learning based on superconductors. Now it is testing learning algorithms for a quantum neural network that can determine the type of wine by its chemical composition and diagnose breast cancer," the report says.

According to the developers, the processor created at MIPT has world-class characteristics: the average lifetime of a qubit is about 14 microseconds, and the average time of one quantum operation is only 50 nanoseconds. These parameters are key to ensuring the high accuracy and stability of quantum computing.

This quantum computer is a logical continuation of the previous developments of Russian physicists, in which they conducted experiments with simpler quantum computers based on five and eight quantum bits. The key difference of the new system is not only the number of qubits, but also the fact that the scientists have switched from a one-dimensional architecture to a two-dimensional arrangement of computing units of the computer.

"This is a big step forward for our laboratory and for the entire scientific community involved in quantum research in Russia. The work demonstrates not only our ability to show new results at the world level, but also promises significant progress in the practical application of quantum technologies, as we always strive to test our devices on real tasks," added MIPT Professor Oleg Astafiev, whose words are quoted by the press service of the university.

This year, Astafiev and his colleagues expect to create an even more complex machine based on 16 superconducting qubits. Its development will bring Russian physicists closer to the creation of computing systems based on a hundred or more qubits, capable of solving complex problems that have practical applications. The creation of such computers is the main task of the Russian roadmap for the development of quantum computing

Quantum Computing Roadmap

This quantum computer was created by specialists from MIPT and other leading scientific centers in Russia as part of the roadmap for the development of quantum computing, developed by Rosatom State Corporation and accepted for implementation in the second half of 2019. As part of the roadmap, Russian scientists are working on the creation of quantum computers on several technological bases, including those based on superconductors, ions, cold atoms and photons.

 

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Forum software started completely fucking with me. The new is: I write a post, hit the post button, and the post disappears. Good